izpis_h1_title_alt

Zasnova translacije bioloških modelov v SBML zapis
OSOLIN, TIMOTEJ (Author), Moškon, Miha (Mentor) More about this mentor... This link opens in a new window, Mraz, Miha (Co-mentor)

.pdfPDF - Presentation file, Download (2,28 MB)

Abstract
Sistemska biologija, kot pomemben člen v verigi številnih področij pri raziskovanju v medicini, uporablja poleg ostalih tehnik tudi kreiranje in urejanje raznovrstnih bioloških modelov. Pri tem tudi izkorišča prednosti objektno orientiranega modeliranja in programskih orodij, namenjenih izdelavi takih modelov. Na Univerzi v Ljubljani so tako razvili knjižnico, imenovano SysBio, kot pomoč pri ustvarjanju bioloških modelov. Za izdelavo knjižnice je bil uporabljen objektno orientiran Modelica programski jezik, ki pa je na področju sistemske biologije in njej sorodnih ved sorazmerno redek. Tako je za kompatibilnost z ostalimi, pogosteje uporabljenimi orodji, potrebna pretvorba v zapis, ki ga ta orodja podpirajo. Poznamo več različnih oblik zapisa, toda v sistemski biologiji je najbolj razširjen zapis SBML (angl. Systems Biology Markup Language). V pričujočem delu predstavimo razvoj programa, ki omogoča translacijo iz jezika Modelica v zapis SBML. Translacijo demonstriramo na enostavnem modelu metabolne poti, ki jo uspešno pretvorimo iz Modelica v SBML zapis.

Language:Slovenian
Keywords:sistemska biologija, SysBio, SBML zapis, Modelica, translacija, biološki modeli
Work type:Bachelor thesis/paper (mb11)
Organization:FRI - Faculty of computer and information science
Year:2016
Views:325
Downloads:269
Metadata:XML RDF-CHPDL DC-XML DC-RDF
 
Average score:(0 votes)
Your score:Voting is allowed only to logged in users.
:
Share:AddThis
AddThis uses cookies that require your consent. Edit consent...

Secondary language

Language:English
Title:Translation of biological models to an SBML notation
Abstract:
Systems biology is one of the important fields of study that is helping medicine with its breakthroughs. Amongst other techniques it uses object oriented modelling and corresponding software tools for creation of such models. University of Ljubljana developed a library, named SysBio, as a vital utility for developing biological models. The library was developed using object oriented Modelica programming language, which is relatively rare in the field of systems biology and its related fields. Therefore a translation to a more known format is necessary to ensure the compatibility with the most popular development tools in this field. There are many different types of formats, however SBML (Systems Biology Markup Language) is the most widespread format in systems biology. In the following work we present the development of software, which enables the translation from Modelica language to a SBML format. We demonstrate such translation on a simple model of metabolic pathway, which is successfully converted from Modelica to SBML format.

Keywords:systems biology, SysBio, SBML format, Modelica, translation, biologic models

Similar documents

Similar works from RUL:
Similar works from other Slovenian collections:

Comments

Leave comment

You have to log in to leave a comment.

Comments (0)
0 - 0 / 0
 
There are no comments!

Back