Chemical characterization of lipophilic and hydrophilic extractives in typical wood tissues of European larch (Larix decidua Mill.), such as sapwood, heartwood, knot and branch segments is presented. The analysis indicated similar
lipophilic structure of all tissues, while the content of hydrophilic phenolic compounds in individual tissues proved to be significantly different. The highest phenolic concentrations were determined in knotwood, which classifies it as suitable raw material for large scale production of bioactive compounds with high added value.