Details

Uporaba nanomaterialov MXene na razvijajočih se bioloških in biomedicinskih področjih
ID Kutin, Jaka (Author), ID Drobne, Damjana (Mentor) More about this mentor... This link opens in a new window

.pdfPDF - Presentation file, Download (865,15 KB)
MD5: C399C2C4CA921AF2A5F08D249F4B67F9

Abstract
V diplomskem delu so predstavljeni obetavni nanomateriali MXene, ki združujejo redke kombinacije lastnosti, kot so električna in kovinska prevodnost ter hidrofilnost in biokompatibilnost. Po strukturi so karbidi, nitridi in karbonitridi prehodnih kovin s splošno formulo Mn+1 Xn Tx , kjer "M" predstavlja kation prehodne kovine, "X" ogljik ali dušik, "T" pa končno površinsko funkcionalno skupino. Fizikalno-kemijske lastnosti MXenov so neposredno povezane z njihovo sintezo, ki jo glede na smer gradnje delimo na tri pristope: "top-down", "up-bottom" ter "bottom-up". Za preučitev in razvoj aplikacij je pomembno poznavanje delovanja materialov na različnih bioloških ravneh. Na molekularni ravni MXeni zaradi svoje visoke specifične površine in Van der Waalsovih sil s proteini tvorijo posebno strukturo – proteinsko korono, prav tako tvorijo interakcije z nukleinskimi kislinami in lipidi. Na celični in tkivni ravni MXeni tvorijo reaktivne kisikove spojine, ki delujejo citotoksično in protibakterijsko. V primerjavi z nanomateriali iz družine grafenov so MXeni manj citotoksični in bolj biokompatibilni, kar jim skupaj z možnostjo površinske funkcionalizacije ter elektro-fototermičnih lastnosti omogoča širši spekter delovanja na različnih področjih. V biomedicini ponujajo možnost uporabe za dostavo zdravil, fototermalno terapijo tumorjev in celjenje kroničnih ran. V bioinženirstvu pa so uporabni kot občutljivi biosenzorji ter komponente v 3D-tisku, biološkem slikanju in ločevalnih membranah.

Language:Slovenian
Keywords:nanomateriali, nanotehnologija, 2D materiali, MXene, biološka reaktivnost
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:BF - Biotechnical Faculty
Year:2026
PID:20.500.12556/RUL-185886 This link opens in a new window
COBISS.SI-ID:288659715 This link opens in a new window
Publication date in RUL:22.08.2026
Views:107
Downloads:43
Metadata:XML DC-XML DC-RDF
:
Copy citation
Share:Bookmark and Share

Secondary language

Language:English
Title:Nanomaterials MXenes as a Tool in Emerging Biological and Biomedical Technologies
Abstract:
The thesis presents promising MXenes nanomaterials that exhibit a rare synergy of properties, such as electrical and metallic conductivity, hydrophilicity and biocompatibility. Structurally, they are carbides, nitrides and carbonitrides of transition metals, with the general formula Mn+1 Xn Tx, where "M" represents a transition metal cation, "X" carbon or nitrogen, and "T" a final surface functional group. The physicochemical properties of MXenes are directly related to their synthesis, which is divided into three approaches depending on the direction of construction: "top-down", "up-bottom" and "bottom-up". To evaluate and develop potential applications, it is essential to know the functioning of materials at different biological levels. At the molecular level, MXenes, due to their high specific surface area and Van der Waals forces, form a special structure — the protein corona. They also form interactions with nucleic acids and lipids. At the cellular and tissue level, MXenes form reactive oxygen species, which have cytotoxic and antibacterial effects. Compared to graphene-family nanomaterials, they are less cytotoxic and more biocompatible, which, together with the possibility of surface functionalization and electro-photothermal properties, opens a wider spectrum of applications in various fields. In biomedicine, they offer the possibility of use for drug delivery, photothermal therapy of tumors and healing of chronic wounds. In bioengineering, they are used as sensitive biosensors and as components in 3D printing, biological imaging and separation membranes.

Keywords:nanomaterials, nanotechnology, 2D materials, MXene, biological reactivity

Similar documents

Similar works from RUL:
Similar works from other Slovenian collections:

Back