One-step copper-assisted synthesis of ▫$\alpha$▫-(styrylsulfonyl)amides via ▫$SO_2$▫ incorporation under visible light

Petek, Nejc (author), Opatz, Till (author)

α-(Styrylsulfonyl)amides and their related ester analogs are an important class of substances that have been widely used as precursors toward bioactive compounds. While most existing methods for the preparation of related compounds include either multiple steps or the use of precious metals, the method presented in this paper utilizes copper and visible light to produce α-(styrylsulfonyl)amides and α-(styrylsulfonyl)esters from α-bromoamides or esters, SO$_2$ and styrenes in moderate to high yield in a single step. The mechanism of the newly developed method is investigated and likely differs from related methods for the photocatalyzed fixation of SO$_2$ into organic scaffolds.

• Language: English
• Keywords: photoredox catalysis, sulfur dioxide, sulfones, copper catalysis, copper complexes
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: FKKT - Faculty of Chemistry and Chemical Technology
• Publication status: Published
• Publication version: Version of Record
• Year: 2025
• Number of pages: 7 str.
• Numbering: Vol. , iss. , art. e70196
• PID: 20.500.12556/RUL-175827
• UDC: 547.551.52:544.526.5
• ISSN on article: 1615-4150
• DOI: 10.1002/adsc.70196
• COBISS.SI-ID: 255761411
• Publication date in RUL: 10.11.2025

Record is a part of a journal

• Title: Advanced Synthesis & Catalysis
• Publisher: Wiley-VCH Verlag GmbH
• ISSN: 1615-4150
• COBISS.SI-ID: 22726149

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Keywords: fotoredoks kataliza, žveplov dioksid, sulfoni, bakrova kataliza, bakrovi kompleksi