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Impact of changes in antihypertensive medication on treatment intensity at hospital discharge and 30 days afterwards
ID
Japelj, Nuša
(
Avtor
),
ID
Kerec Kos, Mojca
(
Avtor
),
ID
Jošt, Maja
(
Avtor
),
ID
Knez, Lea
(
Avtor
)
PDF - Predstavitvena datoteka,
prenos
(869,32 KB)
MD5: 131E3159F15F841C39E60326445870CF
URL - Izvorni URL, za dostop obiščite
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1376002/full
Galerija slik
Izvleček
Introduction: Little is known about the cumulative effect of changes in antihypertensive medications on treatment intensity. This study analyzed how changes in antihypertensive medications affect the intensity of antihypertensive treatment at hospital discharge and 30 days afterwards. Methods: A prospective observational study of 299 hospitalized adult medical patients with antihypertensive therapy was conducted. The effect of medication changes on treatment intensity was evaluated by the Total Antihypertensive Therapeutic Intensity Score (TIS). Results: At discharge, antihypertensive medications were changed in 62% of patients (184/299), resulting in a very small median reduction in TIS of −0.16. Treatment intensity was reduced more with increasing number of antihypertensive medications at admission, whereas it increased with elevated inpatient systolic blood pressure. Thirty days after discharge, antihypertensive medications were changed in 37% of patients (88/239) resulting in a median change in TIS of −0.02. Among them, 90% (79/88) had already undergone a change at discharge. The change in treatment intensity after discharge was inversely correlated with a change at discharge. Discussion: Changes in antihypertensive medication frequently occurred at discharge but had a minimal impact on the intensity of antihypertensive treatment. However, these adjustments exposed patients to further medication changes after discharge, evidencing the need for treatment reassessment in the first month post-discharge.
Jezik:
Angleški jezik
Ključne besede:
hypertension
,
antihypertensive agents
,
hospitalization
,
patient discharge
,
continuity of patient care
Vrsta gradiva:
Članek v reviji
Tipologija:
1.01 - Izvirni znanstveni članek
Organizacija:
FFA - Fakulteta za farmacijo
Status publikacije:
Objavljeno
Različica publikacije:
Objavljena publikacija
Leto izida:
2024
Št. strani:
10 str.
Številčenje:
Vol. 15, article 1376002
PID:
20.500.12556/RUL-160059
UDK:
615.225:616.12
ISSN pri članku:
1663-9812
DOI:
10.3389/fphar.2024.1376002
COBISS.SI-ID:
204037891
Datum objave v RUL:
14.08.2024
Število ogledov:
59
Število prenosov:
0
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Objavi na:
Gradivo je del revije
Naslov:
Frontiers in pharmacology
Skrajšan naslov:
Front Pharmacol
Založnik:
Frontiers Media
ISSN:
1663-9812
COBISS.SI-ID:
29551833
Licence
Licenca:
CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:
http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:
To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Sekundarni jezik
Jezik:
Slovenski jezik
Ključne besede:
odpust bolnika
,
kontinuiteta oskrbe bolnika
,
zdravila
,
antihipertenzivi
,
hospitalizacija
Projekti
Financer:
ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
Številka projekta:
P1-0189
Naslov:
Farmacevtska tehnologija: od dostavnih sistemov učinkovin do terapijskih izidov zdravil pri otrocih in starostnikih
Financer:
ARIS - Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije
Številka projekta:
P3-0360
Naslov:
Celostna obravnava alergijskih bolezni in astme v Sloveniji: od epidemiologije do genetike
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