Gallium(III) complexes with 1,3-pdta-type of ligands : the influence of an alkyl substituent in 1,3-propanediamine chain and the metal counter cation on the structural properties of the complex

Pantović, Bojana V. (author), Ašanin, Darko P. (author), Perdih, Franc (author), Radanović, Dušanka D. (author), Turel, Iztok (author), Djuran, Miloš I. (author), Glišić, Biljana Đ. (author)

The hexadentate 1,3-propanediamine-N,N,N’,N’-tetraacetate (1,3-pdta$^{4−}$) and (±)-1,3-pentanediamine-N,N,N’,N’-tetraacetate (1,3-pndta$^{4−}$) ligands were used for the synthesis of two new gallium(III) complexes, Na[Ga(1,3-pdta)]⋅3H$_2$O (1) and Ba[Ga(1,3-pndta)]$_2$⋅3H$_2$O (2). Complexes 1 and 2 were characterized by IR and NMR ($^1$H and $^{13}$C) spectroscopy and single crystal X-ray diffraction analysis. The obtained results have shown that both hexadentate 1,3-pdta$^{4−}$ and 1,3-pndta$^{4−}$ ligands are coordinated to gallium(III) ion through the two nitrogen and four carboxylate oxygen atoms. Both complexes show significant octahedral distortion since the mean angular deviation is nearly four degrees per angle. However, the octahedral distortion of complex 2 is lower than of 1, as indicated by the ΣΔ(O$_h$) values (48° and 49° versus 53°, respectively). The binding interactions of the complexes 1 and 2 with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) were studied by fluorescence emission spectroscopy. Both complexes can bind to the serum albumin reversibly, while their affinity to ct-DNA is rather low.

• Language: English
• Keywords: gallium(III) complexes, diaminopolycarboxylate ligands, spectroscopy, X-ray diffraction analysis, DNA/BSA interactions
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: FKKT - Faculty of Chemistry and Chemical Technology
• Publication status: Published
• Publication version: Version of Record
• Year: 2024
• Number of pages: 10 str.
• Numbering: Vol. 258, art. 117045
• PID: 20.500.12556/RUL-158208
• UDC: 546.681
• ISSN on article: 0277-5387
• DOI: 10.1016/j.poly.2024.117045
• COBISS.SI-ID: 196415491
• Publication date in RUL: 29.05.2024

Record is a part of a journal

• Title: Polyhedron
• Shortened title: Polyhedron
• Publisher: Elsevier
• ISSN: 0277-5387
• COBISS.SI-ID: 26153984

Licences

• License: CC BY-NC 4.0, Creative Commons Attribution-NonCommercial 4.0 International
• Link: http://creativecommons.org/licenses/by-nc/4.0/
• Description: A creative commons license that bans commercial use, but the users don’t have to license their derivative works on the same terms.

Secondary language

• Language: Slovenian
• Keywords: galijevi(III) kompleksi, diaminopolikarboksilatni ligandi, spektroskopija, rentgenska difrakcijska analiza, interakcije DNA/BSA