Gallium(III) complexes with 1,3-pdta-type of ligands : the influence of an alkyl substituent in 1,3-propanediamine chain and the metal counter cation on the structural properties of the complex

Pantović, Bojana V. (avtor), Ašanin, Darko P. (avtor), Perdih, Franc (avtor), Radanović, Dušanka D. (avtor), Turel, Iztok (avtor), Djuran, Miloš I. (avtor), Glišić, Biljana Đ. (avtor)

The hexadentate 1,3-propanediamine-N,N,N’,N’-tetraacetate (1,3-pdta$^{4−}$) and (±)-1,3-pentanediamine-N,N,N’,N’-tetraacetate (1,3-pndta$^{4−}$) ligands were used for the synthesis of two new gallium(III) complexes, Na[Ga(1,3-pdta)]⋅3H$_2$O (1) and Ba[Ga(1,3-pndta)]$_2$⋅3H$_2$O (2). Complexes 1 and 2 were characterized by IR and NMR ($^1$H and $^{13}$C) spectroscopy and single crystal X-ray diffraction analysis. The obtained results have shown that both hexadentate 1,3-pdta$^{4−}$ and 1,3-pndta$^{4−}$ ligands are coordinated to gallium(III) ion through the two nitrogen and four carboxylate oxygen atoms. Both complexes show significant octahedral distortion since the mean angular deviation is nearly four degrees per angle. However, the octahedral distortion of complex 2 is lower than of 1, as indicated by the ΣΔ(O$_h$) values (48° and 49° versus 53°, respectively). The binding interactions of the complexes 1 and 2 with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) were studied by fluorescence emission spectroscopy. Both complexes can bind to the serum albumin reversibly, while their affinity to ct-DNA is rather low.

• Jezik: Angleški jezik
• Ključne besede: gallium(III) complexes, diaminopolycarboxylate ligands, spectroscopy, X-ray diffraction analysis, DNA/BSA interactions
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: FKKT - Fakulteta za kemijo in kemijsko tehnologijo
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2024
• Št. strani: 10 str.
• Številčenje: Vol. 258, art. 117045
• PID: 20.500.12556/RUL-158208
• UDK: 546.681
• ISSN pri članku: 0277-5387
• DOI: 10.1016/j.poly.2024.117045
• COBISS.SI-ID: 196415491
• Datum objave v RUL: 29.05.2024

Gradivo je del revije

• Naslov: Polyhedron
• Skrajšan naslov: Polyhedron
• Založnik: Elsevier
• ISSN: 0277-5387
• COBISS.SI-ID: 26153984

Licence

• Licenca: CC BY-NC 4.0, Creative Commons Priznanje avtorstva-Nekomercialno 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-nc/4.0/deed.sl
• Opis: Licenca Creative Commons, ki prepoveduje komercialno uporabo, vendar uporabniki ne rabijo upravljati materialnih avtorskih pravic na izpeljanih delih z enako licenco.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: galijevi(III) kompleksi, diaminopolikarboksilatni ligandi, spektroskopija, rentgenska difrakcijska analiza, interakcije DNA/BSA