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Antifungal effect of polymethyl methacrylate resin base with embedded Au nanoparticles
ID
Marić, Ivan
(
Author
),
ID
Zore, Anamarija
(
Author
),
ID
Rojko, Franc
(
Author
),
ID
Sever Škapin, Andrijana
(
Author
),
ID
Štukelj, Roman
(
Author
),
ID
Učakar, Aleksander
(
Author
),
ID
Vidrih, Rajko
(
Author
),
ID
Veselinović, Valentina
(
Author
),
ID
Gotić, Marijan
(
Author
),
ID
Bohinc, Klemen
(
Author
)
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https://www.mdpi.com/2079-4991/13/14/2128
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Abstract
Full and partial restorations in dentistry must replicate the characteristics of the patient’s natural teeth. Materials must have good mechanical properties and be non-toxic and biocompatible. Microbes, which can form biofilms, are constantly in contact with restorations. In this study, we investigate how well Candida albicans adheres to a polymethyl methacrylate (PMMA) resin base with gold (Au) nanoparticles. We synthesized Au nanoparticles and characterized them. The average size of Au nanoparticles embedded in PMMA was 11 nm. The color difference ∆E between PMMA and PMMA/Au composites was 2.7 and was still esthetically acceptable to patients. PMMA/Au surfaces are rougher and more hydrophilic than pure PMMA surfaces, and the isoelectric point of both types of surfaces was 4.3. Above the isoelectric point, PMMA/Au surfaces are more negatively charged than PMMA surfaces. The added Au nanoparticles decreased the tensile strength, while the hardness did not change significantly. Adhesion measurements showed that PMMA surfaces modified with Au nanoparticles reduced the extent of microbial adhesion of Candida albicans.
Language:
English
Keywords:
fungal adhesión
,
C. albicans
,
polymethyl methacrylate resin
,
Au
,
surface properties
,
composites
Work type:
Article
Typology:
1.01 - Original Scientific Article
Organization:
ZF - Faculty of Health Sciences
BF - Biotechnical Faculty
Publication status:
Published
Publication version:
Version of Record
Publication date:
01.01.2023
Year:
2023
Number of pages:
15 str.
Numbering:
Vol. 13, iss. 14, art. 2128
PID:
20.500.12556/RUL-152752
UDC:
66
ISSN on article:
2079-4991
DOI:
10.3390/nano13142128
COBISS.SI-ID:
159528707
Publication date in RUL:
06.12.2023
Views:
693
Downloads:
115
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Record is a part of a journal
Title:
Nanomaterials
Shortened title:
Nanomaterials
Publisher:
MDPI
ISSN:
2079-4991
COBISS.SI-ID:
523286297
Licences
License:
CC BY 4.0, Creative Commons Attribution 4.0 International
Link:
http://creativecommons.org/licenses/by/4.0/
Description:
This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Secondary language
Language:
Slovenian
Keywords:
adhezija gliv
,
C. albicans
,
polimetilmetakrilat
,
Au
,
lastnosti površine
,
kompoziti
Projects
Funder:
ARRS - Slovenian Research Agency
Project number:
P2-0273-2019
Name:
Gradbeni objekti in materiali
Funder:
ARRS - Slovenian Research Agency
Project number:
P3-0388-2022
Name:
Mehanizmi varovanja zdravja
Funder:
ARRS - Slovenian Research Agency
Project number:
J7-2595-2020
Name:
Modulacija polifenolnega profila v sadju s trajnostnimi fizikalnimi poobiralnimi postopki
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