Antifungal effect of polymethyl methacrylate resin base with embedded Au nanoparticles

Marić, Ivan (avtor), Zore, Anamarija (avtor), Rojko, Franc (avtor), Sever Škapin, Andrijana (avtor), Štukelj, Roman (avtor), Učakar, Aleksander (avtor), Vidrih, Rajko (avtor), Veselinović, Valentina (avtor), Gotić, Marijan (avtor), Bohinc, Klemen (avtor)

Full and partial restorations in dentistry must replicate the characteristics of the patient’s natural teeth. Materials must have good mechanical properties and be non-toxic and biocompatible. Microbes, which can form biofilms, are constantly in contact with restorations. In this study, we investigate how well Candida albicans adheres to a polymethyl methacrylate (PMMA) resin base with gold (Au) nanoparticles. We synthesized Au nanoparticles and characterized them. The average size of Au nanoparticles embedded in PMMA was 11 nm. The color difference ∆E between PMMA and PMMA/Au composites was 2.7 and was still esthetically acceptable to patients. PMMA/Au surfaces are rougher and more hydrophilic than pure PMMA surfaces, and the isoelectric point of both types of surfaces was 4.3. Above the isoelectric point, PMMA/Au surfaces are more negatively charged than PMMA surfaces. The added Au nanoparticles decreased the tensile strength, while the hardness did not change significantly. Adhesion measurements showed that PMMA surfaces modified with Au nanoparticles reduced the extent of microbial adhesion of Candida albicans.

• Jezik: Angleški jezik
• Ključne besede: fungal adhesión, C. albicans, polymethyl methacrylate resin, Au, surface properties, composites
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: ZF - Zdravstvena fakulteta ; BF - Biotehniška fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Datum objave: 01.01.2023
• Leto izida: 2023
• Št. strani: 15 str.
• Številčenje: Vol. 13, iss. 14, art. 2128
• PID: 20.500.12556/RUL-152752
• UDK: 66
• ISSN pri članku: 2079-4991
• DOI: 10.3390/nano13142128
• COBISS.SI-ID: 159528707
• Datum objave v RUL: 06.12.2023

Gradivo je del revije

• Naslov: Nanomaterials
• Skrajšan naslov: Nanomaterials
• Založnik: MDPI AG
• ISSN: 2079-4991
• COBISS.SI-ID: 523286297

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: adhezija gliv, C. albicans, polimetilmetakrilat, Au, lastnosti površine, kompoziti