Paracetamol is an analgesic and antipyretic drug used in many pharmaceuticals alone or in combination with other substances. In this research, I analysed the amount of paracetamol left in expired drug samples and in one out of four cases, the concentration of paracetamol was actually lower than prescribed. I also quantitively separated and determined other substances in drug samples, where they were present. I expanded the research onto the analysis of the degradation of paracetamol in different stressful conditions, such as low temperature, high temperature, acidic and alkaline pH, with the purpose of evalution degradation for use in further determination methods. Results showed that the most intensive degradation of paracetamol is in alkaline pH at a high temperature, whereas it degrades slower in acidic pH.
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