Introduction: Tendinopathy of knee flexors is an injury of the proximal tendons of these muscles. It was firstly described in 1988 as ''hamstring syndrome''. Clinically it is rarely an injury with a specific onset event; it usually appears with physical activity as a progressing pain in the proximal posterior part of the thigh near the buttocks. This type of tendinopathy is often wrongly diagnosed or missed altogether. Aetiology has yet to be thoroughly described. Athletes that run a lot suffer from this injury most often. Recent research shows a possible correlation between diabetes and tendinopathy. Tendinopathy of knee flexors is currently most commonly treated with the traditional conservative approach with focus on eccentric training of knee flexors. Purpose: The purpose of this review was to find out the best conservative approaches in the treatment of patients with hamstring tendinopathy, either with physiotherapeutic or other recognized techniques. Methods: PubMed and PEDro were used to search for appropriate research articles with keywords ''hamstring tendinopathy''. Inclusion criteria were randomized control trials and clinical trials, access to full text of the article as well as that the article was published in 2010 or after. Exclusion criteria included literature reviews and other non-research articles, research including patients with other tendinopathies and publish date prior to 2010. Following the initial review of search results, 2 retrospective research articles were included due to small amount of randomized controlled and clinical trials. Results: Laser therapy and extracorporeal shockwave therapy are more efficient in comparison to the traditional approach. Clear proof for efficiency of traditional approach does not exist. Possible treatment also includes injections of platelet-rich plasma or whole blood, both showed similar effect. Two retrospective studies showed promising results in treatment with corticosteroid injections. Discussion and conclusion: Results show efficiency of laser therapy and extracorporeal shockwave therapy, but they are yet to be available in public healthcare on a larger scale. Traditional approach with emphasis on eccentric exercise stays the standard treatment for now, although its scientific foundation should be more thoroughly researched. Possible effective treatment also includes local injections of platelet-rich plasma, whole blood, or corticosteroids. Currently, there isn't enough research done for a quality literature review.
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