Introduction: Schizophrenia is a severe mental illness characterized by delusions and hallucinations, impaired speech, lack of motivation, social withdrawal, and cognitive impairment. The cornerstone in the treatment of schizophrenia is antipsychotic medication, which is most effective in reducing positive symptoms, while having minimal effect on negative symptoms and cognitive impairment, suggesting a need for new treatment strategies. In the general population, aerobic exercise has been shown to have many beneficial effects on individuals’ cognitive functioning. Purpose: The purpose of this diploma thesis was to determine the effects of aerobic exercise on cognitive function in people with schizophrenia based on a literature review. Methods: We used a descriptive method with a literature review. The literature was searched in PubMed and PEDro using the keywords »aerobna vadba AND shizofrenija AND kognicija« and »aerobic exercise AND schizophrenia AND cognition«. Studies were selected if they met the following inclusion criteria: randomized controlled trials, clinical trials, studies published after 2012, articles in Slovenian or English, studies evaluating the effects of aerobic exercise on cognitive function of people with schizophrenia. Results: Six randomized controlled trials were included in the review. Three studies examined the effects of aerobic exercise in combination with cognitive training on cognitive performance, two studies compared the effects of aerobic exercise and antipsychotics with antipsychotic treatment alone, and one study compared the effects of aerobic exercise with balance and stretching exercises. All studies showed that aerobic exercise can improve cognitive performance in people with schizophrenia, but only in four studies were these effects statistically significant. Discussion and conclusion: Based on the literature review, it can be concluded that aerobic exercise has potential positive effects on cognitive performance in people with schizophrenia. However, further research is needed to confirm these effects. Future research should include a larger number of participants, a longer duration of intervention, and an appropriate control group, and monitor the effects of aerobic exercise over a longer period. Aerobic exercise should be used in the treatment of schizophrenia only as a supportive method, together with antipsychotics and psychotherapy.
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