Introduction: Myasthenia gravis is an autoimmune neuromuscular disease characterized by muscle weakness and increased muscle fatigue due to reduced neuromuscular transmission. Among the most commonly used scales for measuring outcomes in clinical trials are the Quantitative Myasthenia Gravis and the Myasthenia Gravis Activity of Daily Living scales in patients with myasthenia gravis. Purpose: The purpose of the research is to determine whether there is a correlation between the results of the Quantitative Myasthenia Gravis scale and the Myasthenia Gravis Activity of Daily Livings scale in patients with myasthenia gravis. Methods: In the research we included 20 adult patients with a confirmed diagnosis of myasthenia gravis, who are already regularly treated at the Clinical Institute for Clinical Neurophysiology for the treatment of the disease. After written consent to participate, we took important data on gender, age, body weight, height, body mass index, disease stage and other non-neurological diseases. The patients were informed about the testing procedure and evaluated using a Quantitative Myasthenia Gravis scale and an Myasthenia Gravis Activity of Daily Living scale. Given the normal distribution of the data, the correlation between the results of the two scales was calculated using Pearson's correlation. Results: Patients with myasthenia gravis, who scored a lower number of points on the Quantitative Myasthenia Gravis scale, also scored a lower number of points on the Myasthenia Gravis Activity of Daily Living scale. The correlation between the scales is moderate to high (r = 0,5858). The results showed that the result of the Quantitative Myasthenia Gravis scale is also affected by non-neurological diseases, which falsely show a worse state of myasthenia gravis, so this must be taken into account in the analyses. Discussion and conclusion: The correlation between the scales is moderate to high. It should be noted here that patients with non-neurological diseases, which mainly affect the quantitive assessment, and less so on daily activities, must be excluded.The reason may be that patients adapt more easily to the daily activities themselves, but they can not perform individual functions during the measurement.
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