Your browser does not allow JavaScript!
JavaScript is necessary for the proper functioning of this website. Please enable JavaScript or use a modern browser.
Open Science Slovenia
Open Science
DiKUL
slv
|
eng
Search
Browse
New in RUL
About RUL
In numbers
Help
Sign in
Discovery of a novel bat lyssavirus in a long-fingered bat (Myotis capaccinii) from Slovenia
ID
Černe, Danijela
(
Author
),
ID
Hostnik, Peter
(
Author
),
ID
Toplak, Ivan
(
Author
),
ID
Presetnik, Primož
(
Author
),
ID
Maurer Wernig, Jedrt
(
Author
),
ID
Kuhar, Urška
(
Author
)
PDF - Presentation file,
Download
(1,14 MB)
MD5: 6DF547344A8B328BDDADAC72F45B161D
URL - Source URL, Visit
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0011420
Image galllery
Abstract
Lyssaviruses are the causative agents of rabies, a zoonotic, fatal disease that is thought to be ancestral to bats. In the last decade, the detection of bat associated lyssaviruses is increasing also in Europe. Within a retrospective bat associated lyssavirus surveillance study a total of 225 dead bats of 21 bat species were collected in Slovenia between 2012 and 2019 and tested by specific real-time RT-PCR method. The first lyssavirus positive sample in bats in Slovenia was detected using the real-time RT-PCR, the fluorescent antibody test, and next generation sequencing, while the rabies tissue culture inoculation test was unsuccessful due to sample degradation and storage conditions. The nearly complete genome of Divača bat lyssavirus from Slovenia consists of 11,871 nucleotides and reflects the characteristic gene organization known for lyssaviruses, encoding the five viral proteins. Phylogenetic analysis of Divača bat lyssavirus revealed that it belongs to phylogroup I lyssaviruses and is most closely related to Kotalahti bat lyssavirus (KBLV) with 87.20% nucleotide and 99.22% amino acid identity. Together with KBLV, Khujand virus, European bat lyssavirus 2, Bakeloh bat lyssavirus, and Aravan virus, Divača bat lyssavirus was detected in the genus Myotis suggesting its key role in the transmission and maintenance of certain lyssaviruses.
Language:
English
Keywords:
real-time polymerase chain reaction
,
lyssaviruses
,
bats
,
rabies virus
,
phylogenetic analysis
,
Europe
,
zoonoses
,
nucleotides
,
species delimitation
Work type:
Article
Typology:
1.01 - Original Scientific Article
Organization:
VF - Veterinary Faculty
Publication status:
Published
Publication version:
Version of Record
Year:
2023
Number of pages:
12 str.
Numbering:
Vol. 17, iss. 6, art. e0011420
PID:
20.500.12556/RUL-147544
UDC:
636.09.578
ISSN on article:
1935-2735
DOI:
10.1371/journal.pntd.0011420
COBISS.SI-ID:
157448451
Publication date in RUL:
07.07.2023
Views:
452
Downloads:
75
Metadata:
Cite this work
Plain text
BibTeX
EndNote XML
EndNote/Refer
RIS
ABNT
ACM Ref
AMA
APA
Chicago 17th Author-Date
Harvard
IEEE
ISO 690
MLA
Vancouver
:
Copy citation
Share:
Record is a part of a journal
Title:
PLoS neglected tropical diseases
Shortened title:
PLoS negl. trop. dis.
Publisher:
PLOS
ISSN:
1935-2735
COBISS.SI-ID:
29974745
Licences
License:
CC BY 4.0, Creative Commons Attribution 4.0 International
Link:
http://creativecommons.org/licenses/by/4.0/
Description:
This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Projects
Funder:
Other - Other funder or multiple funders
Funding programme:
Administration of the Republic of Slovenia for Food Safety, Veterinary Sector, and Plant Protection
Funder:
ARRS - Slovenian Research Agency
Project number:
P4-0092
Name:
Zdravje živali, okolje in varna hrana
Similar documents
Similar works from RUL:
Similar works from other Slovenian collections:
Back