Alzheimer's disease is the most common degenerative brain disease. Pathological proteins accumulate in the patient's brain and damage neurons. The reduction in the number of neurons results in a decline in cognitive abilities. This leads to difficulties in carrying out daily activities and worsens their quality of life. For this group of patients, regular exercise can have a positive impact on their health. Exercise programmes to improve cognitive abilities include aerobic exercise, exercise to improve muscle performance and balance training. Purpose: The aim of this thesis is to review the literature on the effects of physical exercise on cognitive abilities in patients with Alzheimer's disease. Methods: We used a descriptive method of literature review. The literature was searched in the PubMed and PEDro using different combinations of keywords in English. The search included randomised controlled trials with a PEDro scale of 6 or higher. Results: Five randomised controlled trials that met the inclusion criteria were included in the review. A total of 474 subjects were included in the studies. Exercise programmes included aerobic exercise, exercise to improve muscle performance and balance training. They lasted from 12 to 24 weeks. Most of the studies also assessed activities of daily living in addition to cognitive abilities. In three studies, the control group received usual care, in one study they received a multi-component intervention and in one study they received structured activities. Only two studies showed a statistically significant improvement in cognitive abilities. Discussion and conclusion: Based on the studies reviewed, it can be concluded that a guided exercise programme plays an important role in people with AD, as it can increase their involvement in activities of daily living and improve their overall physical endurance. However, the question remains whether these training programmes are actually effective and can have an impact on improving cognitive abilities. Future research should include a larger number of participants and monitor the effects of exercise over a longer period of time.
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