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Vzroki, oblike in odkrivanje primarne imunske pomankljivosti
ID Hočevar, Domen (Author), ID Narat, Mojca (Mentor) More about this mentor... This link opens in a new window

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Abstract
V delu je predstavljen pojem imunska pomanjkljivost. Ker gre za širok spekter bolezenskih stanj, je v delu podrobneje opisan sklop primarnih imunskih pomanjkljivosti. Te namreč med seboj zaradi lažje preglednosti ločimo v devet podkategorij. Kombinirane T-celične in B-celične pomanjkljivosti, motnje v koncentraciji serumskih protiteles, bolezni imunske regulacije, okvare koncentracije in/ali funkcije fagocitnih celic, okvare signalnih molekul prirojenega imunskega odziva, avtovnetne bolezni, deficiti komplementa, sindromske primarne imunske pomanjkljivosti in fenokopije primarnih imunskih pomanjkljivosti. Ker imajo pomanjkljivosti velik vpliv na vsakodnevno življenje bolnika, je zelo pomembno, da jih čimprej odkrijemo. V ta namen imamo razvitih veliko testov, ki omogočajo zaznavo posameznih pomanjkljivosti. Z njihovo pomočjo lahko posamezniku omogočimo najboljšo obliko zdravljenja, prilagojeno njegovi imunski pomanjkljivosti.

Language:Slovenian
Keywords:primarna imunska pomanjkljivost, oblike primarne imunske pomanjkljivosti, limfociti, diagnostični testi, imunoglobulini
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:BF - Biotechnical Faculty
Year:2022
PID:20.500.12556/RUL-140116 This link opens in a new window
COBISS.SI-ID:125349123 This link opens in a new window
Publication date in RUL:11.09.2022
Views:444
Downloads:134
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Secondary language

Language:English
Title:Causes, types and detection of primary immunodeficiency
Abstract:
In this work I present the concept of immunodeficiency. The concept includes a wide specter of illnesses, however here the focus is on primary immunodeficiency. Since this type of immunodeficiency still includes many different illnesses, there exist nine subcatagories in which we further devide the condition. Predominantly antibody deficiencies T-cell immunodeficiencies or combined immunodeficiencies Syndromic immunodeficiencies Complement defects Phagocytic defects Defects of innate immunity Diseases of immune dysregulation Autoinflammatory disorders Phenocopies of Primary immunodeficiency. The immunodeficiency plays a huge roll in everyday life of the patient, therefor we ought to discover them as early as possible. For this purpose, today, we have many tests at our disposal. With them we can discover specific immunodeficiency, which helps us chose the best treatment for the patient.

Keywords:primary immunodeficiency, types of primary immunodeficiency, lymphocytes, diagnostic, immunoglobulins

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