Biocatalytic process intensification via efficient biocatalyst immobilization, miniaturization, and process integration

Žnidaršič Plazl, Polona (avtor)

Despite their sustainability, the potential of biocatalytic processes in industrial production is far from being realized. The main challenges in this field are the development of highly active, robust, and stable biocatalysts, the efficient regeneration of cofactors, and the prevention of biocatalyst deactivation under harsh industrial conditions. In addition to biocatalyst engineering, efficient enzyme and cell immobilization plays a crucial role in process feasibility. Reactor miniaturization, continuous operation, and integration with in situ product removal, process analytics, and cascade reactions that reduce the number of process steps enable process intensification. Mathematical model–based reactor and process design comprising time-scale analysis and efficient capacity increase can push the boundaries of biocatalytic processes toward industrial requirements. This review highlights the latest trends in efficient biocatalyst immobilization, miniaturization, and process integration to intensify biocatalytic processes.

• Jezik: Angleški jezik
• Ključne besede: microreactor, continuous process, biocatalyst immobilization, reactor design, process intensification
• Vrsta gradiva: Članek v reviji (dk_c)
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: FKKT - Fakulteta za kemijo in kemijsko tehnologijo
• Leto izida: 2021
• Status objave pri reviji: Objavljeno
• Verzija članka: Založnikova različica članka
• Datum objave: 01.12.2021
• Št. strani: Str. 1-8
• Številčenje: Vol. 32
• PID: 20.500.12556/RUL-136180
• UDK: 66.098
• ISSN pri članku: 2452-2236
• DOI: 10.1016/j.cogsc.2021.100546
• COBISS.SI-ID: 73824771
• Datum objave v RUL: 15.04.2022

Gradivo je del revije

• Naslov: Current opinion in green and sustainable chemistry
• Založnik: Elsevier
• ISSN: 2452-2236
• COBISS.SI-ID: 528288537

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 01.12.2021

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: mikroreaktorji, kontinuirni procesi, imobilizacija biokatalizatorjev, načrtovanje reaktorjev, intenzifikacija procesa