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Non-alcoholic fatty liver disease in children
ID
Brecelj, Jernej
(
Avtor
),
ID
Orel, Rok
(
Avtor
)
PDF - Predstavitvena datoteka,
prenos
(769,05 KB)
MD5: 0E4772D8BF29B7F0C677783B45B527EE
URL - Izvorni URL, za dostop obiščite
https://www.mdpi.com/1648-9144/57/7/719
Galerija slik
Izvleček
Background and Objectives: The prevalence of pediatric non-alcoholic fatty liver disease is increasing. A lot of new data are published regularly. Materials and Methods: Original clinical studies, review articles, and guidelines in children were searched for and the most relevant included in this review. Results: A total of 138 retrieved papers were classified into pathogenesis, epidemiology, diagnosis, and treatment. Pathogenesis is currently explained with the "multi hit hypothesis", with complex interactions of genetic and environmental factors which trigger inflammation in steatotic liver. The prevalence is rising. A diagnosis can be made with laboratory tests, imaging, and liver biopsy after the exclusion of other causes of liver steatosis. The mainstay of treatment is lifestyle modification consisting of dietary intervention and increased physical activity. The progression to liver cirrhosis can occur even in children. Conclusions: Non-alcoholic fatty liver disease in children is a part of a metabolic syndrome in the majority of patients. Due to its complex etiology and high prevalence, multidisciplinary teams, together with public health professionals, should be involved in its treatment.
Jezik:
Angleški jezik
Ključne besede:
pediatric fatty liver disease
,
diet
,
lifestyle modification
,
obesity
,
physical activity
Vrsta gradiva:
Članek v reviji
Tipologija:
1.02 - Pregledni znanstveni članek
Organizacija:
MF - Medicinska fakulteta
Status publikacije:
Objavljeno
Različica publikacije:
Objavljena publikacija
Leto izida:
2021
Št. strani:
15 str.
Številčenje:
Vol. 57, iss. 7, art. 719
PID:
20.500.12556/RUL-136005
UDK:
616-053.2
ISSN pri članku:
1648-9144
DOI:
10.3390/medicina57070719
COBISS.SI-ID:
81204483
Datum objave v RUL:
06.04.2022
Število ogledov:
657
Število prenosov:
96
Metapodatki:
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Objavi na:
Gradivo je del revije
Naslov:
Medicina
Založnik:
MDPI
ISSN:
1648-9144
COBISS.SI-ID:
6754623
Licence
Licenca:
CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:
http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:
To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Začetek licenciranja:
16.07.2021
Sekundarni jezik
Jezik:
Slovenski jezik
Ključne besede:
otroška maščobna jetrna bolezen
,
prehrana
,
sprememba življenjskega sloga
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