New insights into antibacterial and antifungal properties, cytotoxicity and aquatic ecotoxicity of flame retardant PA6/DOPO-derivative nanocomposite textile fibers

Vasiljević, Jelena (author), Štular, Danaja (author), Kalčíková, Gabriela (author), Zajc, Janja (author), Šobak, Matic (author), Demšar, Andrej (author), Tomšič, Brigita (author), Simončič, Barbara (author), Čolović, Marija (author), Šelih, Vid Simon (author), Jerman, Ivan (author)

The aim of this study was to evaluate the antibacterial and antifungal activity, cytotoxicity, leaching, and ecotoxicity of novel flame retardant polyamide 6 (PA6) textile fibers developed by our research group. The textile fibers were produced by the incorporation of flame-retardant bridged 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) derivative (PHED) in the PA6 matrix during the in situ polymerization process at concentrations equal to 10 and 15 wt% (PA6/10PHED and PA6/15PHED, respectively). Whilst the nanodispersed PHED provided highly efficient flame retardancy, its biological activity led to excellent antibacterial activity against Escherichia coli and Staphylococcus aureus, as well as excellent antifungal activity against Aspergillus niger and Candida albicans. The results confirmed leaching of the PHED, but the tested leachates did not cause any measurable toxic effect to the duckweed Lemna minor. The in vitro cytotoxicity of the leached PHED from the PA6/15PHED sample was confirmed for human cells from adipose tissue in direct and prolonged contact. The targeted biological activity of the organophosphinate flame retardant could be beneficial for the development of PA6 textile materials with multifunctional properties and the low ecotoxicity profile, while the PHED’s leaching and cytotoxicity limit their application involving the washing processes and direct contact with the skin.

• Language: English
• Keywords: polyamide 6, textile filament, DOPO derivative, antibacterial activity, antifungal activity, ecotoxicity, cytotoxicity
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: NTF - Faculty of Natural Sciences and Engineering; FKKT - Faculty of Chemistry and Chemical Technology
• Publication status: Published
• Publication version: Version of Record
• Year: 2021
• Number of pages: 17 str.
• Numbering: Vol. 13, iss. 6, art. 905
• PID: 20.500.12556/RUL-135199
• UDC: 677
• ISSN on article: 2073-4360
• DOI: 10.3390/polym13060905
• COBISS.SI-ID: 55570947
• Publication date in RUL: 28.02.2022

Record is a part of a journal

• Title: Polymers
• Shortened title: Polymers
• Publisher: MDPI
• ISSN: 2073-4360
• COBISS.SI-ID: 517951257

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 15.03.2021

Secondary language

• Language: Slovenian
• Keywords: poliamid 6, tekstilni filament, DOPO derivat, antibakterijsko delovanje, protiglivično delovanje, ekotoksičnost, citotoksičnost