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Pretvorba karbonilnih spojin z nekaterimi nukleofili
ID Jeretina, Tina (Author), ID Jereb, Marjan (Mentor) More about this mentor... This link opens in a new window

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Abstract
Karbonilne spojine so v naravi zelo razširjene, hkrati pa so nepogrešljive tudi sintetsko. To so spojine, ki imajo ogljikov atom z dvojno vezjo vezan na kisikov atom. Karbonilno skupino najdemo v molekulah aldehidov, ketonov, karboksilnih kislinah in njihovih derivatih ter v ogljikovih hidratih in drugod. V svojem delu sem se ukvarjala z različnimi pretvorbami karbonilnih spojin. Aldehidi in ketoni najpogosteje sodelujejo v nukleofilnih adicijah, karboksilne kisline in njihovi derivati pa v nukleofilnih substitucijah. Opisala sem reakcije nastanka in uporabnost para-kinonskih metidov, saj so njihovi vmesni produkti pomembni v številnih bioloških in kemijskih procesih. Ena pomembnejših reakcij pri kateri se tvori vezi ogljik‒ogljik, je Michaelova reakcija. Spoznala pa sem se tudi z reakcijami na inone, ki imajo karbonilno skupino vezano ob trojni vezi.

Language:Slovenian
Keywords:karbonilne spojine, nukleofilna adicija, nukleofilna substitucija, Michaelova reakcija
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:FKKT - Faculty of Chemistry and Chemical Technology
Year:2021
PID:20.500.12556/RUL-130132 This link opens in a new window
COBISS.SI-ID:82894851 This link opens in a new window
Publication date in RUL:10.09.2021
Views:1615
Downloads:92
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Secondary language

Language:English
Title:Transformations of carbonyl compounds by some nucleophiles
Abstract:
Carbonyl compounds are very widespread in nature and synthetically they are indispensable. Their carbon atom is connected to an oxygen atom by a double bond. Carbonyl group can be found in compounds of aldehydes, ketones, carboxylic acids and their derivatives, carbohydrates and other. With my work I focused on different conversions of carbonyl compounds. Aldehydes and ketones most frequently participate in nucleophilic additions, yet carboxylic acids and their derivatives in nucleophilic substitutions. I described formation reactions and use of para-quinone methides because their intermediate products are very important in many biological and chemical processes. One of more important reactions, in which carbon bond is formed, is the Michael reaction. I also learned about reactions with ynones, which have carbonyl group next to the triple bond.

Keywords:carbonyl group, nucleophilic addition, nucleophilic substitution, Michael reaction

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