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Vpliv hrane na nastanek avtoimunskih bolezni.
ID Skrbinek, Mojca (Author), ID Narat, Mojca (Mentor) More about this mentor... This link opens in a new window, ID Bukovnik, Urška (Co-mentor)

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Abstract
Število bolnikov z avtoimunskimi motnjami v zadnjih desetletjih močno narašča. Večina bolezni je še vedno neozdravljivih in na mnogo dejavnikov, ki prispevajo k njihovemu razvoju, ne moremo vplivati, vseh pa sploh še ne poznamo. Hrana je ena izmed komponent, za katero je dokazano, da lahko odločilno prispeva k začetku in nadaljnjemu razvoju bolezni. Porušena homeostaza in kronično vnetje črevesja lahko skupaj z genetskimi in epigenetskimi dejavniki ter napačno dieto vodi do nastanka različnih avtoimunskih motenj. Tako lahko pomanjkanje vitamina D vodi v razvoj multiple skleroze, prevelika količina soli lahko pripomore k razvoju revmatoidnega artritisa, mlečni izdelki z visoko vsebnostjo β-kazeina prispevajo k razvoju diabetesa tipa 1 ter gluten lahko sproži nastanek celiakije. Veliko raziskav je pokazalo tudi, da lahko mikotoksini dodatno oslabijo delovanje imunskega sistema ter tako pripomorejo k razvoju avtoimunskih stanj.

Language:Slovenian
Keywords:avtoimunske bolezni, vitamin D, NaCl, beta-kazein, gluten, mikotoksini
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:BF - Biotechnical Faculty
Publisher:[M. Skrbinek]
Year:2020
PID:20.500.12556/RUL-119717 This link opens in a new window
UDC:606:616:601.4:577.27:577.161.2(043.2)
COBISS.SI-ID:31240451 This link opens in a new window
Publication date in RUL:11.09.2020
Views:1653
Downloads:244
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Secondary language

Language:English
Title:Effect of food on the development of autoimmune diseases
Abstract:
The number of patients with autoimmune disorders have been rising sharply in recent decades. Most diseases are still incurable and many of the factors that contribute to their development cannot be influenced and many of them are still unknown. Food is one of the components that has been shown to make a significant contribution to the onset and further development of the disease. Disrupted homeostasis and chronic inflammation of the gut, along with genetic and epigenetic factors and poor diet, can lead to the development of various autoimmune disorders. Thus, vitamin D deficiency can lead to the development of multiple sclerosis, too much salt can contribute to the development of rheumatoid arthritis, milk products with high β-casein content may cause type 1 diabetes, and gluten can trigger celiac disease. Many studies have also shown that mycotoxins can further weaken the immune system and thus contribute to the development of autoimmune conditions.

Keywords:autoimmune disease, vitamin D, NaCl, beta-casein, gluten, mycotoxins

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