Uporaba nanofibrilirane celuloze za izdelavo hidrogelov

Stante, Luka (avtor), Poljanšek, Ida (mentor), Vek, Viljem (komentor)

Cilj diplomskega dela je bila priprava hidrogelov iz celuloznih nanofibril z navadno alkalno obdelavo in študij vpliva koncentracije bazične raztopine NaOH na njihovo tvorbo. Z različnimi koncentracijami alkalne raztopine smo želeli določiti optimalno razmerje med suspenzijo NFC, NaOH in vodo za tvorbo obstojnega hidrogela. K hidrogelom smo dodali kostanjev tanin, z namenom tvorbe hidrogela, ki bi imel antibakterijsko delovanje, saj je znano, da tanini dobro zavirajo rast bakterij. Iz tako pripravljenih, kompaktnih in stabilnih kompozitnih hidrogelov smo izmerili in izračunali maso, volumen, gostoto, vsebnost vode, poroznost in vsebnost suhe snovi hidrogela. Najboljše lastnosti in obstojnost so imeli hidrogeli, kjer je bila k 20 g NFC (1,3 %) dodana bazična raztopina v masnem razmerju 20/60 in 30/50 NaOH in destilirane vode. Antibakterijsko delovanje tanina je bilo moč opaziti že pri 1 % dodanega tanina glede na skupno maso hidrogela. S povečevanjem koncentracije tanina nad 3 % glede na maso NFC suspenzije smo negativno vplivali na kompaktnost hidrogelov. Tako smo ugotovili, da dodajanje tanina v koncentracijah, večjih kot 3 %, ni smiselno, saj ogrozimo kompaktnost hidrogela, antibakterijske lastnosti ostanejo enake, poleg tega pa se veliko tanina iz hidrogela izpere.

• Jezik: Slovenski jezik
• Ključne besede: hidrogel, nanofibrilirana celuloza, tanin, antibakterijsko delovanje
• Vrsta gradiva: Diplomsko delo/naloga
• Tipologija: 2.11 - Diplomsko delo
• Organizacija: BF - Biotehniška fakulteta
• Založnik: [L. Stante]
• Leto izida: 2019
• PID: 20.500.12556/RUL-112709
• UDK: 630*813.2
• COBISS.SI-ID: 3127177
• Datum objave v RUL: 07.11.2019

STANTE, Luka, 2019, Uporaba nanofibrilirane celuloze za izdelavo hidrogelov [na spletu]. Diplomsko delo. L. Stante. [Dostopano 6 maj 2025]. Pridobljeno s: https://repozitorij.uni-lj.si/IzpisGradiva.php?lang=slv&id=112709

Sekundarni jezik

• Jezik: Angleški jezik
• Naslov: Use of nanofibrillated cellulose for the manufacture of hydrogels

Izvleček

It is known from previous research that the suspension of nanofibrillated cellulose is easily transformed into stable hydrogel with the process of mercerization. The goal of this work was the preparation of hydrogels from cellulose nanofibrils with basic alkaline processing, and a study of the effect that the concentration of the NaOH has on their formation. With differing concentrations of the alkaline solution the optimal correlation between the suspension of NFC, NaOH and H2O for the formation of a durable hydrogel was determined. To attain a hydrogel with antibiotic properties the chestnut tannin was added, as it is known that these tannins inhibit the growth of bacteria efficiently. From the stable and compact composite hydrogels thus produced we measured and calculated the mass, volume, density, water content, porosity and the content of the dry matter of the hydrogel. The hydrogels with optimal properties and durability were those with the mass ratio of NaOH and distilled water 20/60, 30/50. The antibacterial activity of tannin was visible as soon as 1% of tannin was added to a joint mass of hydrogel (100g). With increasing the concentration of tannin above 3% in reference to the mass of the NFC suspension, we negatively affected the compactness of hydrogels. Therefore, we concluded that adding tannins in a concentration above 3% is irrational, since it reduces the compactness of hydrogels, the antibacterial properties remain unchanged and the excess of tannin is flushed away.

• Ključne besede: hydrogel, nanofibrillated cellulose, tannin, antibacterial activity