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Prisotnost halogenskih vezi v kokristalih in soleh diatrizoične kisline
Drešar, Zala (Author), Perdih, Franc (Mentor) More about this mentor... This link opens in a new window

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Abstract
Z vrsto različnih reakcij sem preverjala vpliv topila in razmerja reaktantov na reakcije diatrizoične kisline z ostalimi reagenti. Z rentgensko praškovno analizo in rentgensko strukturno analizo sem preverjala nastanek kokristalov oziroma soli ter prisotnost halogenskih vezi v trdninah. Kokristal je enotna kristalinična snov, katere kristalno rešetko sestavljajo nevtralne komponente in so pri sobnih pogojih v trdnem agregatnem stanju. Uporabni so na različnih področjih, predvsem v farmaciji, saj so lahko kemijsko bolj stabilni, imajo nižjo temperaturo tališča, se hitreje raztapljajo in imajo višjo topnost. Diatrizoična kislina se uporablja kot kontrastno sredstvo, ki se uporablja pri rentgenskih slikanjih za vizualizacijo notranjih organov in ožilja.

Language:Slovenian
Keywords:halogenska vez, kokristali, diatrizoična kislina, rentgenska praškovna difrakcija
Work type:Bachelor thesis/paper (mb11)
Tipology:2.11 - Undergraduate Thesis
Organization:FKKT - Faculty of Chemistry and Chemical Technology
Year:2019
COBISS.SI-ID:1538392003 This link opens in a new window
Views:450
Downloads:142
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Secondary language

Language:English
Title:Presence of halogen bonds in cocrystals and salts of diatrizoic acid
Abstract:
The influence of solvents and ratio of reactants in many different reactions of diatrizoic acid with other reactants has been tested. The appearance of cocrystals and presence of halogen bonds in co-crystals was analysed by powder X-ray diffraction and single crystal structural X-ray diffraction. Cocrystals are solids that are crystalline single phase materials, they form a unique crystalline structure with unique properties, such as higher chemical stability, lower melting point, fast dissolving and higher solubility. Cocrystals can be used in many different fields and are also commonly used in pharmacy as they have unique properties. Diatrizoic acid is also used as a contrast medium in x-ray scan for visualization of inner organs and vessels.

Keywords:halogen bond, cocrystals, diatrizoic acid, powder X-ray diffraction

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