Preračun sterilne tlačne posode, vključene v proces pranja tehnološke opreme v farmacevtski industriji

Feuš, Urban (author), Čepon, Gregor (mentor), Boltežar, Miha (co-mentor)

V zaključnem delu je opisan postopek konstruiranja sterilne tlačne posode za farmacevtsko industrijo, skladno s standardom EN 13445. Tlačna posoda bo uporabljena za sistem pranja tehnološke opreme. Zaradi dezinfekcije posode s paro, je zahtevana obratovalna temperatura + 150 °C in najvišji dovoljeni tlak + 4 bare. Najprej so predstavljene teoretične osnove tlačne opreme, ki so potrebne za nadaljnje razumevanje. Nato so podrobneje opisane zahteve, ki jih mora izbrani material tlačne opreme zadostiti. Obravnavane so tudi možne oblike posod in njihov namen. Sledi podroben preračun vseh sestavnih delov posode skladno s konstrukcijskimi zahtevami. Izračunan je najmanjši potreben testni tlak, s katerim moramo obremeniti posodo, da zadostimo zahtevam standarda. Grafično so prikazane relativne vrednosti potrebnih in uporabljenih debelin sestavnih delov posode. S preračunom je dokazano, da je posoda primerna za varno uporabo.

• Language: Slovenian
• Keywords: konstruiranje, preračuni, tlačne posode, pravilniki, tlačna oprema, farmacija, standard EN 13445
• Work type: Final paper
• Typology: 2.11 - Undergraduate Thesis
• Organization: FS - Faculty of Mechanical Engineering
• Place of publishing: Ljubljana
• Publisher: [U. Feuš]
• Year: 2019
• Number of pages: XVII, 78 f.
• PID: 20.500.12556/RUL-109394
• UDC: 621.772.4:519.6:615.4(043.2)
• COBISS.SI-ID: 16776219
• Publication date in RUL: 01.09.2019

Secondary language

• Language: English
• Title: Calculation of sterile pressure vessel involved in the washing process of technological equipment in pharmaceutical industry

Abstract

The final thesis describes the procedure for the design of a sterile pressure vessel for the pharmaceutical industry in accordance with EN 13445. The pressure vessel will be used in the washing process of technological equipment. The disinfection of the vessel with steam requires the operating temperature of + 150 °C and the maximum allowable pressure in the vessel of + 4 bars. First, the theoretical basics of pressure equipment needed for further understanding are presented. Then the requirements that the selected material must meet are described in detail. Possible shapes of vessels and their purpose are explained. The calculation of the components of the pressure vessel according to design requirements is carried out in great detail. The minimum required test pressure, with which the vessel is tested to conform to standard is calculated. The relative values of calculated and used thicknesses are graphically presented. The calculation proves that the vessel is suitable for safe use.

• Keywords: design, calculation, pressure vessels, pharmacy, standard EN 13445