1. Structural and functional characterization of an organometallic ruthenium complex as a potential myorelaxant drugTomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Jakob Kljun, Iztok Turel, Evelyne Benoit, Robert Frangež, 2020, izvirni znanstveni članek Ključne besede: organoruthenium nitrophenanthroline complex, acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, mouse neuromuscular system, ruthenium, muscle relaxation, physiology, glutathione transferase
Celotno besedilo (datoteka, 1,45 MB) Gradivo ima več datotek! Več... |
2. Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probesStane Pajk, Damijan Knez, Urban Košak, Maja Zorović, Xavier Brazzolotto, Nicolas Coquelle, Florian Nachon, Jacques-Philippe Colletier, Marko Živin, Jure Stojan, Stanislav Gobec, 2020, izvirni znanstveni članek Ključne besede: butyrylcholinesterase, inhibitor, probe, fluorescence
Celotno besedilo (datoteka, 1,60 MB) Gradivo ima več datotek! Več... |
3. Treatment of canine cognitive dysfunction with novel butyrylcholinesterase inhibitorMaja Zakošek, Sonja Prpar Mihevc, Malan Štrbenc, Urban Košak, Ilija German Ilić, Jurij Trontelj, Simon Žakelj, Stanislav Gobec, Darja Pavlin, Gregor Majdič, 2021, izvirni znanstveni članek Ključne besede: Alzheimer’s disease, butyrylcholinesterase, butyrylcholinesterase inhibitor, canine cognitive dysfunction, canine dementia scale, dogs
Celotno besedilo (datoteka, 1,34 MB) Gradivo ima več datotek! Več... |
4. Structural isomerism and enhanced lipophilicity of pyrithione ligands of organoruthenium(II) complexes increase inhibition on AChE and BuChEJerneja Kladnik, Samuel Ristovski, Jakob Kljun, Andrea Defant, Ines Mancini, Kristina Sepčić, Iztok Turel, 2020, izvirni znanstveni članek Ključne besede: Alzheimer’s disease, acetylcholinesterase, butyrylcholinesterase, cholinesterase inhibitor, molecular docking, organoruthenium(II) complexes, pyrithione derivatives
Celotno besedilo (datoteka, 1,28 MB) Gradivo ima več datotek! Več... |
5. 4-phenethyl-1-propargylpiperidine-derived dual inhibitors of butyrylcholinesterase and monoamine oxidase BTjaša Mazej, Damijan Knez, Anže Meden, Stanislav Gobec, Matej Sova, 2021, izvirni znanstveni članek Ključne besede: Alzheimer's disease, butyrylcholinesterase, monoamine oxidase B, inhibitors, multi-target-directed ligands, multifunctional ligands
Celotno besedilo (datoteka, 3,88 MB) Gradivo ima več datotek! Več... |
6. Polyfunctionalized α-phenyl-tert-butyl(benzyl)nitronesDaniel Diez-Iriepa, Damijan Knez, Stanislav Gobec, Isabel Iriepa, Cristóbal de los Ríos, Isaac Bravo, Francisco López-Muñoz, José Marco-Contelles, Dimitra Hadjipavlou-Litina, 2022, izvirni znanstveni članek Ključne besede: butyrylcholinesterase, free radical scavengers, neuroprotection, α-phenyl-tert-butyl(benzyl)nitrones, in vitro digestion, extractable and bound phenolics
Celotno besedilo (datoteka, 2,12 MB) Gradivo ima več datotek! Več... |
7. From tryptophan-based amides to tertiary aminesAnže Meden, Damijan Knez, Xavier Brazzolotto, Florian Nachon, Jose Dias, Jurij Svete, Jure Stojan, Uroš Grošelj, Stanislav Gobec, 2022, izvirni znanstveni članek Ključne besede: cholinesterase inhibitors, Alzheimer's disease, butyrylcholinesterase, carbamate, pseudoirreversible inhibition
Celotno besedilo (datoteka, 4,55 MB) Gradivo ima več datotek! Več... |
8. Novel organoruthenium(II) complex C1 selectively inhibits butyrylcholinesterase without side effects on neuromuscular transmissionTomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Iztok Turel, Robert Frangež, 2023, izvirni znanstveni članek Ključne besede: organoruthenium(II) complex, acetylcholinesterase, butyrylcholinesterase, mouse neuromuscular system, ruthenium, Alzheimer disease, neurodegenerative diseases
Celotno besedilo (datoteka, 3,74 MB) Gradivo ima več datotek! Več... |
9. 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseasesDamijan Knez, Anže Meden, Anja Pišlar, Janko Kos, Simon Žakelj, Jure Stojan, Stanislav Gobec, José Marco-Contelles, 2023, izvirni znanstveni članek Ključne besede: quinolylnitrone, butyrylcholinesterase, monoamine oxidase B, Alzheimer's disease, multifunctional ligands, 6-hydroxydopamine model, passive avoidance task, novel object recognition
Celotno besedilo (datoteka, 3,96 MB) Gradivo ima več datotek! Več... |
