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2. Discovery of a new drug-like series of OGT inhibitors by virtual screeningElena Maria Loi, Tihomir Tomašič, Cyril Balsollier, Kevin van Eekelen, Matjaž Weiss, Martina Gobec, Matthew G Alteen, David J. Vocadlo, Roland J. Pieters, Marko Anderluh, 2022, izvirni znanstveni članek Ključne besede: O-GlcNAc transferase, OGT inhibitors, virtual screening, pharmaceutical chemistry
Celotno besedilo (datoteka, 10,66 MB) Gradivo ima več datotek! Več... |
3. A fine-tuned lipophilicity/hydrophilicity ratio governs antibacterial potency and selectivity of bifurcated halogen bond-forming NBTIsAnja Kolarič, Maja Kokot, Martina Hrast, Matjaž Weiss, Irena Zdovc, Jurij Trontelj, Simon Žakelj, Marko Anderluh, Nikola Minovski, 2021, izvirni znanstveni članek Ključne besede: antibacterials, drug discovery, DNA gyrase inhibitors, topoisomerase IV inhibitors, intercalators, novel bacterial topoisomerase inhibitors, topoisomerase II inhibitors, intercalating agents
Celotno besedilo (datoteka, 6,80 MB) Gradivo ima več datotek! Več... |
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5. Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacyMaja Kokot, Matjaž Weiss, Irena Zdovc, L. Šenerović, Natasa Radakovic, Marko Anderluh, Nikola Minovski, Martina Hrast, 2023, izvirni znanstveni članek Ključne besede: NBTIs, DNA gyrase, Topoisomerase IV, antibacterials, MRSA, hERG inhibition, in vivo efficacy
Celotno besedilo (datoteka, 3,61 MB) Gradivo ima več datotek! Več... |
6. Intracellular hydrolysis of small-molecule O-linked N-acetylglucosamine transferase inhibitors differs among cells and is not required for its inhibitionElena Maria Loi, Matjaž Weiss, Stane Pajk, Martina Gobec, Tihomir Tomašič, Roland J. Pieters, Marko Anderluh, 2020, izvirni znanstveni članek Ključne besede: ester hydrolysis, inhibitor, O-GlcNAc transferase, OGT inhibitor
Celotno besedilo (datoteka, 1,90 MB) Gradivo ima več datotek! Več... |
7. Inhibition of O-GlcNAc transferase alters the differentiation and maturation process of human monocyte derived dendritic cellsMatjaž Weiss, Marko Anderluh, Martina Gobec, 2021, izvirni znanstveni članek Ključne besede: O-GlcNAcylation, O-GlcNAc transferase (OGT), monocyte derived DCs, OSMI-1, immunometabolism, pharmaceutical chemistry
Celotno besedilo (datoteka, 2,84 MB) Gradivo ima več datotek! Več... |
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9. Structurally optimized potent dual-targeting NBTI antibacterials with an enhanced bifurcated halogen-bonding propensityMaja Kokot, Matjaž Weiss, Irena Zdovc, Martina Hrast, Marko Anderluh, Nikola Minovski, 2021, izvirni znanstveni članek Ključne besede: NBTIs, DNA gyrase, topoisomerase IV, bifurcated halogen bonds, dual targeting
Celotno besedilo (datoteka, 2,92 MB) Gradivo ima več datotek! Več... |
10. New quinolinone O-GlcNAc transferase inhibitors based on fragment growthMatjaž Weiss, Elena Maria Loi, Maša Sterle, Cyril Balsollier, Tihomir Tomašič, Roland J. Pieters, Martina Gobec, Marko Anderluh, 2021, izvirni znanstveni članek Ključne besede: O-GlcNAc, O-GlcNAc transferase, protein glycosylation, fragments growth, molecular docking
Celotno besedilo (datoteka, 1,37 MB) Gradivo ima več datotek! Več... |
