1. Organoruthenium complexes with benzo-fused pyrithiones overcome platinum resistance in ovarian cancer cellsJerneja Kladnik, James P. C. Coverdale, Jakob Kljun, Hilke Burmeister, Petra Lippman, Francesca G. Ellis, Alan M. Jones, Ingo Ott, Isolda Romero-Canelón, Iztok Turel, 2021, izvirni znanstveni članek Ključne besede: ruthenium, pyrithione, resistance to chemotherapy, cancer, ovarian, thioredoxin Celotno besedilo (datoteka, 3,10 MB) Gradivo ima več datotek! Več... |
2. Structural and functional characterization of an organometallic ruthenium complex as a potential myorelaxant drugTomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Jakob Kljun, Iztok Turel, Evelyne Benoit, Robert Frangež, 2020, izvirni znanstveni članek Ključne besede: organoruthenium nitrophenanthroline complex, acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, mouse neuromuscular system, ruthenium, muscle relaxation, physiology, glutathione transferase Celotno besedilo (datoteka, 1,45 MB) Gradivo ima več datotek! Več... |
|
4. Binding kinetics of ruthenium pyrithione chemotherapeutic candidates to human serum proteins studied by HPLC-ICP-MSKatarina Marković, Radmila Milačič, Stefan Marković, Jerneja Kladnik, Iztok Turel, Janez Ščančar, 2020, izvirni znanstveni članek Ključne besede: ruthenium-based chemotherapeutics, drug candidates, pyrithione, kinetics study, human serum, speciation analysis, CLC monolithic chromatography, CIM Protein G, DEAE disks, UV spectrometry, isotope dilution inductively coupled plasma mass spectrometry Celotno besedilo (datoteka, 2,80 MB) Gradivo ima več datotek! Več... |
5. Conformationally driven Ru(II)-catalyzed multiple ortho-C-H bond activation in diphenylpyrazine derivatives in waterSara Hrovat, Miha Drev, Uroš Grošelj, Franc Perdih, Jurij Svete, Bogdan Štefane, Franc Požgan, 2020, izvirni znanstveni članek Ključne besede: ruthenium catalysts, heterocycles, green chemistry, microwave, direct arylation Celotno besedilo (datoteka, 2,15 MB) Gradivo ima več datotek! Več... |
6. Catalytic stereoconvergent synthesis of homochiral β‑CF$_3$, β‑SCF$_3$, and β‑OCF$_3$ benzylic alcoholsAndrej Emanuel Cotman, Pavel A. Dub, Maša Sterle, Matic Lozinšek, Jaka Dernovšek, Živa Zajec, Anamarija Zega, Tihomir Tomašič, Dominique Cahard, 2022, izvirni znanstveni članek Ključne besede: adaptive crystals, asymmetric catalysis, density functional calculations, drug design, fluorine, hydrogenation, kinetic resolution, ruthenium, alcohols, catalysts, crystals, ketones, stereoselectivity Celotno besedilo (datoteka, 2,08 MB) Gradivo ima več datotek! Več... |
7. Novel organoruthenium(II) complex C1 selectively inhibits butyrylcholinesterase without side effects on neuromuscular transmissionTomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Iztok Turel, Robert Frangež, 2023, izvirni znanstveni članek Ključne besede: organoruthenium(II) complex, acetylcholinesterase, butyrylcholinesterase, mouse neuromuscular system, ruthenium, Alzheimer disease, neurodegenerative diseases Celotno besedilo (datoteka, 3,74 MB) Gradivo ima več datotek! Več... |
8. Ruthenium complexes show potent inhibition of AKR1C1, AKR1C2, and AKR1C3 enzymes and anti-proliferative action against chemoresistant ovarian cancer cell lineJakob Kljun, Renata Pavlič, Eva Hafner, Tanja Lipec, Sara Moreno-Da Silva, Primož Tič, Iztok Turel, Tomaž Büdefeld, Jure Stojan, Tea Lanišnik-Rižner, 2022, izvirni znanstveni članek Ključne besede: ruthenium complexes, synthesis, crystal structure, anticancer, aldo-keto reductase, enzyme inhibition Celotno besedilo (datoteka, 1,85 MB) Gradivo ima več datotek! Več... |
9. Hydrogen-bonding ability of Noyori–Ikariya catalysts enables stereoselective access to CF$_3$-substituted syn-1,2-diols via dynamic kinetic resolutionMaša Sterle, Matej Huš, Matic Lozinšek, Anamarija Zega, Andrej Emanuel Cotman, 2023, drugi znanstveni članki Ključne besede: asymmetric catalysis, DFT, drug design, fluorine, hydrogenation, kinetic resolution, ruthenium, catalysts, ketones, noncovalent interactions, redox reactions, stereoselectivity Celotno besedilo (datoteka, 2,30 MB) Gradivo ima več datotek! Več... |
10. Catalytic performance of Noyori–Ikariya-type ruthenium complex with tethered syn-ULTAM ligand for the asymmetric transfer hydrogenation of ketonesSimona Hašanová, Jernej Cingl, Tihomir Tomašič, Andrej Emanuel Cotman, 2024, izvirni znanstveni članek Ključne besede: asymmetric synthesis, ruthenium, hydrogenation, alcohol Celotno besedilo (datoteka, 599,43 KB) Gradivo ima več datotek! Več... |