Cholesterol is a lipid molecule that performs many functions in the body. Its biosynthesis and distribution in the body as a non-polar molecule are extremely complex. Packed in lipoproteins travel to the liver, where the main pathway of metabolism and the formation of bile salts take place. Typically, cholesterol in our body originates from two ways. One third of it is consumed with food, and the rest is formed endogenously from the previous acetyl-CoA molecule. People today are more and more likely to experience increased blood cholesterol, as a result of poor diet and an unhealthy way of life. Another possibility for the development of hypercholesterolaemia is an inherited genetic disorder. In this case we talk about so-called familiar hypercholesterolaemia. Gradually, such elevated cholesterol levels can lead to the formation of cardiovascular diseases, which are one of the main causes of death in the developed world. For this reason, it is essential for our health to resolve the elevated cholesterol condition. A healthy diet, which is based primarily on reduced intake of saturated fat, trans fat and cholesterol, is very important. We also need to take care for the proper input of fibers, sterols and functional foods (soybean proteins, berberin, extracts of green tea ...). A healthy lifestyle that includes physical activity, normalization of body weight and reduction of unhealthy habits such as smoking and excessive alcohol consumption, contribute to better results.