The main goal of this diploma thesis is developement of a system for interacting with molecular stuctures in virtual world with the help of depth sensors. We used Oculus Rift 3D glases, Kinect and Leap Motion sensors with Unity game engine. We developed four diferent versions of the aplication. The basic version without sensors, one version for each sensor, and the final version that combines all others. One of more obvious finding is that it is better not to use more sensors at the same time, because they interfere with each other. So it is better to use only one sensor and put more work into it.