The dissertation includes presentation and configuration Palo Alto firewall, firewall of next generation. The aim of dissertation is to provide essential knowledge and innovations, which are brought by the firewall of the latest generation. Reader needs to have the equipment, desire to learn about firewall Palo Alto and has basic computer knowledge. Reader is guided through the part with theory and exercises. The exercises include placing firewall into local network, configuration of interfaces, configuration security policies, configuration translation policies, threat and application recognition, blocking application and decrypt traffic. By reading this dissertation and exercises reader gets essential guidelines for successful firewall preparation. Configuration firewall gives him basics for local network protection. At the end of dissertation you can find solutions to each exercise. Exercises in dissertation include only few functionalities of firewall Palo Alto.