Introduction: Computed tomography is an important diagnostic tool, but is associated with relatively high radiation exposure, especially to radiosensitive organs such as the eye lens. Therefore, optimization of imaging is essential. One of the techniques is organ-based tube current modulation, which reduces exposure of anteriorly located organs by lowering the tube current during the anterior part of the rotation. Purpose: The aim of this thesis is to
analyze the impact of organ-based tube current modulation by Siemens (X-CARE) on radiation dose and image quality in head CT examinations. Methods: The measurements were performed in three parts. First, we analyzed the enstrance skin dose at six points with the anthropomorphic head phantom, and observed whether the dose, in accordance with the
theoretical operation of X-CARE, decreases in the anterior and increases in the posterior part of the head. In the second part, we observed the effect of X-CARE on the distribution of CTDIvol within the phantom using a CTDI phantom. In the third part, based on a retrospective
analysis of CT images of pediatric subjects, we objectively compared the image quality between the routine and X-CARE protocol using computer software and evaluated the
impact of modulation on noise, signal to noise ratio (SNR) and contrast to noise ratio (CNR). In addition, we also analyzed CTDIvol and DLP in these subjects to compare the protocols in a clinical setting. Results: The use of X-CARE in measurements of the entrance skin dose on an anthropomorphic head phantom resulted in a significant reduction in dose to the anterior part of the head, most notably in the glabella and lens (up to 69%), while the dose
to the posterior part of the head increased (22%). Also in measurements in the lateral position of the phantom, the modulation adapted to the position and reduced the dose to the anterior part of the head by approximately 60%. Additional measurements with the CTDI phantom also showed a reduction in dose (CTDIvol and DLP) to the anterior part of the phantom and an increase in dose to the posterior and lateral parts, confirming the expected mode of action
of the X-CARE modulation. Image quality analysis of 60 pediatric head CT examinations showed no statistically significant differences in the standard deviation of CT numbers, SNR or CNR between the compared protocols (p > 0.05). Image quality was comparable for both protocols. Comparison of CTDIvol and DLP in pediatric subjects showed statistically significantly higher CTDIvol and DLP values in examinations performed using X-CARE (p< 0.001) Discussion and conclusion: The results show that the use of the X-CARE
technique allows for dose reduction of anterior structures, such as the lens of the eye, without a statistically significant impact on image quality.
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