Introduction: Computed tomography (CT) begins with a topogram, which provides the automatic tube current modulation (ATCM) system with input data for adjusting tube current. The choice of localizer positioning, anteroposterior (AP), posteroanterior (PA), lateral (LAT), or their combinations, influences the ATCM algorithm's estimation of patient size and consequently affects the radiation dose. Purpose: To determine how different localizer positionings and combinations affect ATCM parameters and radiation dose in chest CT imaging. Methods: Measurements were performed on a PBU60 phantom using a Siemens Somatom Drive CT at Institute of radiology, UMC Ljubljana. A total of 50 acquisitions were performed (n = 10 per combination) across five configurations: AP, PA, LAT, AP+LAT and PA+LAT. CTDIvol and DLP and effective tube current (mAs) were recorded. Statistical analysis was performed using the Kruskal-Wallis test, Wilcoxon test and Pearson correlation coefficient (IBM SPSS V29). Results: The lowest CTDIvol values were measured with the AP+LAT combination (1,81 ± 0,07 mGy), while the highest were recorded with the PA localizer (2,43 ± 0,04 mGy). The difference between AP+LAT and PA+LAT was 15,42 % for CTDIvol (p < 0,001) and 17,29 % for DLP (p < 0,001). Expected CTDIvol and DLP values were statistically significantly higher than actual measured values across all configurations (p < 0,005), reflecting the predictive design of the CARE Dose 4D system. Pearson correlation confirmed a strong positive relationship between effective mAs and both CTDIvol and DLP. SNR values ranged from 1,73 ± 0,22 (PA) to 2,15 ± 0,21 (LAT), and CNR values ranged from 83,91 ± 17,86 (AP+LAT) to 102,48 ± 12,62 (LAT). Despite statistically significant differences in dose parameters across localizer combinations, SNR and CNR differences between most pairs were mostly non-significant. The comparison of AP+LAT and PA+LAT yielded comparable SNR (p = 1,000) and CNR (p = 0,269) values. Discussion and conclusion: The PA localizer overestimates the effective patient diameter due to geometric magnification of the projection, increasing tube current without improving image quality. The AP+LAT combination provides the ATCM algorithm with a more accurate estimate of the elliptical body geometry and achieves the lowest radiation dose. Optimising localizer positioning is a simple measure radiographers can implement without modifying protocols or requiring additional equipment.
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