Introduction: Parkinson's disease is a neurodegenerative disease characterized by gradually progressive motor and non-motor symptoms. The disease significantly affects the daily functioning of the individual, including the field of work. Occupational therapy can help maintain work participation by adjusting work tasks, the work environment and the methods of performing activities. Purpose: To review the existing literature on the topic of work participation of people with Parkinson's disease and identify factors that influence work participation. Methods: A literature review was conducted according to the guidelines of the Joana Briggs Institute. The literature search was conducted in the CINAHL, Web of Science and PubMed databases. Eleven articles published between 2006 and 2023 were included in the final analysis. Results: The work participation of people with Parkinson's disease is influenced by many factors, including progressive motor and non-motor symptoms, disease progression, workplace adaptations, stigma and discrimination. People with Parkinson's disease leave the workplace on average 6 years after diagnosis, and the proportion of employees after ten years from diagnosis is around 10%. Many employees do not wish to express their desire for adjustments in the workplace, even though they would help them maintain employment for a longer period and be more successful at their work. Many employees also do not want their colleagues to find out about the diagnosis, as this would consequently make them less capable and competent. Discussion and conclusion: Early diagnosis of Parkinson's disease has a significant impact on work participation, social inclusion and quality of life, with the proportion of employed people decreasing significantly as the disease progresses, and unemployment is one of the key factors of dissatisfaction with life. Appropriate adjustments to the work environment, such as flexible working hours, task reorganization, use of assistive technology and effective communication between employer and employee, significantly contribute to maintaining employment for people with early- onset Parkinson's disease. A comparison of early-onset Parkinson's disease with Multiple Sclerosis showed some similarities, as both diseases are usually diagnosed between the ages of 20 and 40, during the most active working period, and work participation differs slightly between the two diseases, as they have different course.
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