Sinteza in karakterizacija cinkovih(II) kompleksov z amino alkoholi

Nemec, Katarina (author), Podjed Rihtaršič, Nina (mentor)

Koordinacijske spojine so sestavljene iz centralnega kovinskega atoma ali iona in koordiniranih ligandov. Ta diplomska naloga se osredotoča na koordinacijske spojine cinka(II), pri čemer smo kot izhodišče izbrali [Zn(quin)$_2$(H$_2$O)], v kateri quin− označuje ligand kinaldinat. Ta se na cinkov(II) ion veže N,O-bidentatno kelatno. Izbrali smo ga zaradi močne kelatne vezave s kovinskim ionom, ki omeji število možnih produktov reakcije. Reakcije smo izvajali z naslednjimi amino alkoholi: 2-amino-1-propanol (2a1pOH), 2-amino-2-metil-1-propanol (2a2m1pOH), 2-amino-1-butanol (2a1bOH), 1-amino-2-propanol (1a2pOH), 1-amino-2-metil-2-propanol (1a2m2pOH), 1-amino-2-butanol (1a2bOH). Cilj je bila substitucija koordinirane vode z amino alkoholom. Amino alkoholi so organske spojine z dvema funkcionalnima skupinama, aminsko in hidroksilno, ki obe delujeta kot Lewisovi bazi in se tako lahko vežeta na kovinski ion. Reakcije smo izvedli pri različnih pogojih: v avtoklavu pri 105 °C, pri sobni temperaturi in pri pogojih refluksa. V prvih dveh primerih smo kot topilo uporabili acetonitril, pri reakcijah pod refluksom pa nitrometan. Pri reakcijah smo spreminjali količino amino alkohola in čas sinteze. Rezultati so se med posameznimi amino alkoholi precej razlikovali. Pri reakcijah z 2a1pOH in 2a1bOH se je na cinkov(II) ion vezal en amino alkohol, pri reakcijah z 1a2m2pOH in 1a2bOH pa sta se vezala dva v trans konfiguraciji. Pri 1a2bOH smo poleg trans produkta izolirali tudi cis produkt. Reakcije z 1a2pOH so dale tri različne produkte: koordinacijsko spojino z enim amino alkoholom, koordinacijsko spojino z dvema ter ionsko spojino [Zn(1a2pOH)$_3$]quin$_2$. Reakcija z 2a1pOH je v enem primeru vodila tudi do nastanka koordinacijskega polimera. Pri 2a2m1pOH nismo izolirali nobenega produkta. Dobljene produkte smo karakterizirali z različnimi metodami. Uporabili smo infrardečo (IR) spektroskopijo in jedrsko magnetno resonančno (NMR) spektroskopijo. Kristale, nastale med sintezo, smo analizirali z rentgensko strukturno analizo na monokristalu, ki nam je dala podrobne informacije o strukturi spojine.

• Language: Slovenian
• Keywords: cink, koordinacijska kemija, amino alkoholi, kinaldinat
• Work type: Bachelor thesis/paper
• Typology: 2.11 - Undergraduate Thesis
• Organization: FKKT - Faculty of Chemistry and Chemical Technology
• Year: 2026
• PID: 20.500.12556/RUL-184590
• COBISS.SI-ID: 288485635
• Publication date in RUL: 10.07.2026

Secondary language

• Language: English
• Title: Synthesis and characterization of zinc(II) complexes with amino alcohols

Abstract

Coordination compounds consist of a central metal atom or ion and coordinated ligands. This thesis focuses on the coordination compounds of zinc(II), using [Zn(quin)$_2$(H$_2$O)] as a starting compound, in which quin− denotes the ligand quinaldinate. It binds to the zinc(II) ion in a N,O-bidentate chelating manner. Quinaldinate was chosen because of its strong chelating interaction with the metal ion, which limits the number of possible reaction products. The reactions were carried out with the following amino alcohols: 2-amino-1-propanol (2a1pOH), 2-amino-2-methyl-1-propanol (2a2m1pOH), 2-amino-1-butanol (2a1bOH), 1-amino-2-propanol (1a2pOH), 1-amino-2-methyl-2-propanol (1a2m2pOH), 1-amino-2-butanol (1a2bOH). The goal was to substitute coordinated water with an amino alcohol. Amino alcohols are organic compounds with two functional groups, amino and hydroxyl, both of which can act as Lewis bases and thus bind to a metal ion. The reactions were carried out under different conditions: in an autoclave at 105 °C, at room temperature and under reflux conditions. In the first two cases, acetonitrile was used as a solvent, and nitromethane was used in reflux reactions. The reactions were carried out using different amounts of amino alcohol and different reaction times. The results varied considerably among the individual amino alcohols. In reactions with 2a1pOH and 2a1bOH, one amino alcohol coordinated to the zinc(II) ion, and in reactions with 1a2m2pOH and 1a2bOH, two were bound in a trans configuration. In reactions with 1a2bOH, in addition to the trans product, the cis product was also isolated. Reactions with 1a2pOH yielded three different products: a coordination compound with one amino alcohol, a coordination compound with two, and an ionic compound [Zn(1a2pOH)$_3$]quin$_2$. In one case, the reaction with 2a1pOH also led to the formation of a coordination polymer. With 2a2m1pOH, no product was isolated. The obtained products were characterized by various methods. Infrared (IR) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy were used. The crystals that formed during the synthesis were analyzed by single-crystal X-ray diffraction, which provided detailed information about the structures of the compounds.

• Keywords: zinc, coordination chemistry, amino alcohols, quinaldinate