Definitions of histological abnormalities in inflammatory bowel disease : an ECCO position paper

Feakins, Roger (author), Zidar, Nina (author)

Histological assessment of endoscopic biopsies in inflammatory bowel disease [IBD] plays an important role in clinical management, investigative studies, and clinical trials. Scoring schemes consisting of multiple histological items and offering considerable precision are widely available. However, definitions of histological abnormalities are often inconsistent. Furthermore, interobserver variability for their recognition and assessment may be high. The European Crohn’s and Colitis Organisation [ECCO] formed an expert panel to explore definitions of histological abnormalities in IBD, with the aim of improving the quality of diagnosis and facilitating development of scoring schemes. The process confirmed that the current definitions often have no evidence base and vary between sources. Using available evidence and expert knowledge, the panel produced a series of ECCO consensus position statements on histological features in IBD.

• Language: English
• Keywords: inflammatory bowel disease, histology, definition, ulcerative colitis, Crohn's disease
• Work type: Article
• Typology: 1.02 - Review Article
• Organization: MF - Faculty of Medicine
• Publication status: Published
• Publication version: Version of Record
• Year: 2023
• Number of pages: Str. 175-191
• Numbering: Vol. 18, iss. 2
• PID: 20.500.12556/RUL-183335
• UDC: 616.3
• ISSN on article: 1876-4479
• DOI: 10.1093/ecco-jcc/jjad142
• COBISS.SI-ID: 174627587
• Publication date in RUL: 11.06.2026

Record is a part of a journal

• Title: Journal of Crohn's and colitis
• Publisher: Elsevier
• ISSN: 1876-4479
• COBISS.SI-ID: 512590648

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Keywords: vnetna črevesna bolezen, histologija, definicija, ulcerozni kolitis, Crohnova bolezen