Metilacije in oksidacije 2-pirimidintionov v stabilne kelatne molekule za pripravo novih kovinskih kompleksov bakra in renija

Antonin, Blaž (author), Kljun, Jakob (mentor)

V sklopu magistrskega dela sta bila poleg prej znanih štirih kelatnih 2-pirimidintionov (A) sintetizirana tudi dva nova analoga. Iz njih sem po znanih postopkih pripravil S-metilirane analoge (B) ter oksidirane ustrezne bis-bidentatne disulfidne analoge (D). Metiltiopirimidine sem nato uporabil za pripravo ternarnih bakrovih(I) kompleksov z 1,1'-bis(difenilfosfino)ferocenom (dppf) s splošno fomulo [Cu(dppf)(B)]PF6. Dimerne disulfide D sem uporabil za sintezo trikarbonilnih renijevih(I) koordinacijskih spojin s splošno formulo [(fac-Re(CO)3Cl)2(μ-D)]. Pripravljeni kompleksi so bili okarakterizirani z jedrsko magnetno resonanco (NMR), IR in UV-VIS spektroskopijo, masno spektrometrijo in CHN elementno analizo, nekaterim spojinam pa je bila določena struktura tudi z rentgensko strukturno analizo.

• Language: Slovenian
• Keywords: baker, renij, substituirani pirimidini, disulfidi
• Work type: Master's thesis/paper
• Organization: FKKT - Faculty of Chemistry and Chemical Technology
• Year: 2026
• PID: 20.500.12556/RUL-182620
• Publication date in RUL: 19.05.2026

Secondary language

• Language: English
• Title: Methylations and oxydations of 2-pirimidinethiones to stable chelating molecules for the preparation of new metal complexes of copper and rhenium

Abstract

In this master’s thesis, two new analogues were synthesised in addition to four previously known chelating 2-pyrimidinethiones (A). From these, I prepared S-methylated analogues (B) and oxidised bis-bidentate disulfide analogues (D). I then used methylthiopyrimidines to prepare ternary copper(I) complexes with 1,1'-bis(diphenylphosphino)ferrocene. Dimeric disulfides D were used for the synthesis of tricarbonyl rhenium complexes with the general formula [(fac-Re(CO)3Cl)2(μ-D)]. The prepared complexes were characterised by nuclear magnetic resonance (NMR), IR and UV-VIS spectroscopy, mass spectrometry, CHN elemental analysis, and the structures of some compounds were determined by X-ray structure analysis.

• Keywords: copper, rhenium, substituted pyrimidines, disulfides