Individualizirana optimalna srčna frekvenca pri kritično bolnih bolnikih z atrijsko fibrilacijo : spoznanja iz ehokardiografije in analize fizioloških signalov : raziskovalni podatki, obravnavani v članku

Kolar Kus, Petra (author), D'Angelo, Andrea (author), Žgavc, Borut (author), Podbregar, Lev (author), Mati-Djuraki, Urša (author), Podbregar, Matej (author)

Atrijska fibrilacija (AF) je pogosta pri kritično bolnih bolnikih in je povezana s povečano umrljivostjo. Uporabljata se dve terapevtski strategiji: nadzor ritma in nadzor srčnega utripa (SR). Pri strategiji nadzora SR ostaja optimalni ciljni SR negotova. Cilj te študije je bil razviti in primerjati metode za določanje optimalnega območja SR na podlagi transtorakalne ehokardiografije in analize fizioloških signalov. Glavni izsledek raziskave: Optimalni individualni srčni utrip – opredeljen kot srčni utrip, povezan z maksimalnim srčnim izpustom – je mogoče pri bolnikih z atrijsko fibrilacijo določiti z uporabo ehokardiografije ob postelji ali z analizo fizioloških signalov. Ti pristopi lahko podpirajo individualizirano zdravljenje, usmerjeno v srčni utrip, pri kritično bolnih bolnikih z atrijsko fibrilacijo.

• Language: Slovenian
• Keywords: atrijska fibrilacija, optimalna srčna frekvenca, ehokardiografija, analiza signalov, hemodinamika
• Typology: 2.20 - Research data
• Geographic coverage: Third-level medical ICU in General and Teaching Hospital Celje, Slovenia
• Temporal coverage: March 2023 and September 2025
• Organization: MF - Faculty of Medicine
• Year: 2026
• PID: 20.500.12556/RUL-179165
• Data col. methods: Measurements and tests
• Publication date in RUL: 12.02.2026

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: English
• Title: Individualized optimal heart rate in critically ill atrial fibrillation patients : insights from echocardiography and physiological signal analysis : research data underlying the article

Abstract

Background. Atrial fibrillation (AF) is common in critically ill patients and is associated with increased mortality. Two therapeutic strategies are used: rhythm control and heart rate (HR) control. In the HR‑control strategy, the optimal HR target remains uncertain. The aim of this study was to develop and compare methods for determining the optimal HR range based on transthoracic echocardiography and analysis of physiological signals. Conclusions. The optimal individual HR—defined as the HR associated with maximal cardiac output—can be determined in patients with AF using either bedside echocardiography or analysis of physiological signals. These approaches may support individualized HR‑targeted management in critically ill patients with AF.

• Keywords: atrial fibrillation, optimal heart rate, echocardiography, signal analysis, hemodynamics