Occupational therapy plays a crucial role in the treatment of children with intellectual disabilities and associated conditions, as it aims to improve their occupational performance and quality of life. The American Occupational Therapy Practice Framework (OTPF-4) provides a structured approach to evaluation, intervention, and outcome assessment. Methods: This article presents a case study of a 7-year-old boy with an intellectual disability, visual impairment, and associated genetic and neurological disorders. The intervention was based on OTPF-4 and incorporated elements of a neurodevelopmental approach. The included developing an occupational profile, occupational performance analysis, goal setting, selecting appropriate therapeutic interventions and approaches, implementing therapy, and evaluating outcomes. Results: After one year of occupational therapy intervention, positive results were achieved. The boy showed improvements in social interaction and motor skills, and greater independence in daily occupations (toilet training, eating, and computer use). Dependence on adult assistance decreased, leading to greater participation in social and educational activities. Conclusion: OTPF-4 provides a structured and flexible framework for occupational therapy intervention in children with intellectual disabilities and associated conditions. A client-centered, individualized approach enables greater independence and quality of life. Additionally, interdisciplinary collaboration and family involvement in therapy are also essential.
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