Primerjava DSC določitve polimorfizma sulfapiridina z dvema načinoma merjenja: kompenzacijo moči ter toplotnim tokom

Štojs, Neja (author), Čelan Korošin, Nataša (mentor)

V diplomskem delu sem s pomočjo diferenčne dinamične kalorimetrije (DSC) primerjala termične lastnosti sulfapiridina pri različnih merilnih pogojih in dvema načinoma merjenja: kompenzacijo moči in toplotnim tokom. Glavni poudarek je bil na primerjavi med dvema instrumentoma; starejšim Mettler Toledo DSC1, ki meri po principu toplotnega toka (HF), ter novim Mettler Toledo DSC5+, ki poleg toplotnega toka (HF) omogoča merjenje tudi s kompenzacijo moči (PC).

• Language: Slovenian
• Keywords: sulfapiridin, polimorfizem, DSC, toplotni tok, kompenzacija moči
• Work type: Bachelor thesis/paper
• Organization: FKKT - Faculty of Chemistry and Chemical Technology
• Year: 2025
• PID: 20.500.12556/RUL-176381
• Publication date in RUL: 28.11.2025

Secondary language

• Language: English
• Title: Comparison of DSC Determination of Sulfapyridine Polymorphism Using Two Measurement Methods: Power Compensation and Heat Flow

Abstract

In my thesis, I used differential scanning calorimetry (DSC) to compare the thermal properties of sulfapyridine under different measurement conditions and with two measurement methods: power compensation and heat flow. The main focus was on comparing two instruments: the older Mettler Toledo DSC1, which operates according to the heat flow (HF) principle, and the newer Mettler Toledo DSC5+, which, in addition to heat flow (HF), also allows measurement with power compensation (PC).

• Keywords: sulfapyridine, polymorphism, DSC, heat flow, power compensation