The Irish setter is an energic hunting and family breed, recognized for its mahagony-red coat, elegance and lively temperament. Due to its intelligence and need for exercise, it requires extensive physical and mental stimulation, otherwise behavioral disorders often occur. We are facing challenges related to genetics, health and ethology. This thesis addresses the key hereditary diseases of Irish setters, including hip dysplasia, progressive retinal atrophy, hypothyroidism, epilepsy, osteochondrosis, canine leukocyte adhesion deficiency (CLAD) and gluten-sensitive enteropathy. It also examines the impact of selective breeding on reduced genetic diversity and highlight the importance of genetic testing in breeding management. Special attention is also given to common health problems, such as gastric dilatation-volvulus, allergies, atopic dermatitis and chronic ear infections. It also presents preventive measures that contribute to their management. The ethological perspective emphasizes the importance of exercise, socialization and proper training, as modern urban lifestyle of dog owners often makes it difficult to meet the biological needs of the breed. The long-term welfare of Irish setter dog can only be achieved through carefully planned genetic selection, regular health screening, ethical breeding practices and owner education. Only a holistic approach that connects breeders, veterinarians and owners can ensure the knowledge, welfare and logevity of the breed in the future.
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