In my thesis, I theoretically described the course of classical cross-coupling reactions and then also direct functionalisation using metal catalysts. In the experimental part, I focused on direct functionalisation of C–H bonds using a ruthenium catalyst in the presence of an imidazole directing group. In the first stage, I prepared 1-benzyl-2-phenyl-1H-imidazole, which was then used in further reactions with various aryl halides with different electron-donor or electron-withdrawal properties in the presence of [Ru(p-cimen)Cl2]2 catalyst. To determine the effects on the course of the reaction, I varied the solvents water and toluene as well as addition of ligands KOPiv and PPh3. I found out that in the water the addition of ligands is not necessary and that the monosubstituted product is formed selectively. In toluene, the addition of ligands is necessary, mono- and disubstituted products can be formed. I did not observe any direct correlation between the influence of electron-donor or electron-withdrawal substituents and the course of the reaction.
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