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Vpliv medvrstnih mikrobnih interakcij na pojavljanje in širjenje protimikrobne odpornosti
ID Dowhyj, Rocio (Author), ID Danevčič, Tjaša (Mentor) More about this mentor... This link opens in a new window

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Abstract
Pri uporabi protimikrobnih sredstev se pojavljajo problemi, saj so mikroorganizmi sposobni razviti toleranco oziroma odpornost proti njim, kar zmanjša učinkovitost teh sredstev. Da bi se soočili s to težavo, so bile izvedene številne študije, kjer so proučevali mehanizme razvoja odpornosti mikroorganizmov. Te študije so večinoma vključevale mikroorganizme v monokulturah, medtem ko je v naravi večina mikrobnih populacij heterogenih in mikroorganizmi v njih med seboj vzpostavijo socialne interakcije. Le-te imajo ključno vlogo pri pojavu in širjenju odpornosti. Namen diplomskega dela je preučiti medvrstne mikrobne interakcije in kako le-te vplivajo na odpornost ter s tem poudariti pomembnost nadaljnih raziskav na tem področju. Ugotovitve tovrstnih raziskav bi pripomogle k razvoju personaliziranih terapij, boljših protimikrobnih sredstev in trajnostnih biotehnoloških procesov.

Language:Slovenian
Keywords:Mikrobne interakcije, odpornost, toleranca, protimikrobno sredstvo
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:BF - Biotechnical Faculty
Year:2025
PID:20.500.12556/RUL-171381 This link opens in a new window
COBISS.SI-ID:246661635 This link opens in a new window
Publication date in RUL:24.08.2025
Views:196
Downloads:23
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Secondary language

Language:English
Title:Impact of interspecies interactions on the emergence and spread of antimicrobial resistance
Abstract:
The problem with the use of antimicrobials is that microorganisms can acquire tolerance and resistance, which reduces their effectiveness. To address this problem, many researchers have studied resistance mechanisms, but have mostly focused on monocultures. However, most microbes naturally live in mixed-species communities, where social interactions are established. These interactions play a key role in the emergence and spread of antimicrobial resistance. The aim of this thesis is to examine these interactions and their impact on resistance, thereby highlighting the importance of further research in this area. The findings of such research could make an important contribution to the development of personalized therapies, improved antimicrobial agents, and sustainable biotechnological processes.

Keywords:Microbial interactions, resistance, tolerance, antimicrobial agen

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