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Analiza procesa črpanja v modelu levega prekata človeškega srca s pomožno srčno črpalko
ID Žibert, Karin (Author), ID Bizjan, Benjamin (Mentor) More about this mentor... This link opens in a new window

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Abstract
Pomožne srčne črpalke, znane tudi kot pomožne naprave za srčne bolezni (LVAD), se uporabljajo bodisi kot začasna rešitev pred presaditvijo srca bodisi kot dolgoročna podpora pri terapiji bolnikov s srčnim popuščanjem. Kljub tehnični dovršenosti pa LVAD naprave bistveno spremenijo naravno dinamiko krvnega toka v levem prekatu, kar lahko vodi do številnih zapletov. Za izboljšanje razumevanja toka krvi v srcu z in brez podpore LVAD smo izvedli eksperimentalno študijo s slikovno velocimetrijo delcev (PIV). V okviru raziskave smo opazovali tok modelne tekočine, podobne krvi, pri različnih srčnih frekvencah in iztisnih volumnih v modelu srca. Rezultati PIV analize so hitrostna polja in izpeljane veličine, ki kažejo na značilno razliko med tokovnimi razmerami v zdravem in obolelem srcu. Uporaba LVAD poveča pretok krvi po telesu, vendar spremembe tokovnih razmer niso zgolj pozitivne, pač pa lahko pod določenimi pogoji povečajo tveganje za tvorbo strdkov (trombozo) ali pa razpad rdečih krvničk (hemolizo). Rezultati kažejo, da obratovanje LVAD pri konstantnih vrtljajih ni optimalno, ampak bi se morala vrtilna frekvenca spreminjati glede na potrebe bolnika.

Language:Slovenian
Keywords:pomožne naprave za srčne bolezni, tokovne razmere, srčno popuščanje, slikovna velocimetrija delcev, hematološki zapleti, analiza črpanja krvi
Work type:Master's thesis/paper
Typology:2.09 - Master's Thesis
Organization:FS - Faculty of Mechanical Engineering
Year:2025
Number of pages:XX, 88 str.
PID:20.500.12556/RUL-171240 This link opens in a new window
UDC:621.65:616.126:532.5(043.2)
COBISS.SI-ID:246153475 This link opens in a new window
Publication date in RUL:21.08.2025
Views:476
Downloads:190
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Secondary language

Language:English
Title:Analysis of pumping process in the model of left human heart ventricle with an auxiliary heart pump
Abstract:
Heart assist pumps, known as left ventricular assist devices (LVADs), are used either as a temporary solution before heart transplantation or as long-term therapy for patients with heart failure. Despite their technical sophistication, LVADs significantly alter the natural flow dynamics within the left ventricle, which can lead to various complications. To better understand blood flow in the heart with and without LVAD support, we conducted an experimental study using particle image velocimetry (PIV). In this study, we observed the flow of a blood-analog fluid under different heart rates and stroke volumes in a heart model. The PIV analysis yielded velocity fields and derived quantities that revealed distinct differences between the flow conditions in healthy and failing hearts. While LVAD support increases overall blood flow through the body, the associated changes in flow patterns are not entirely beneficial. Under certain conditions, they may increase the risk of thrombus formation or red blood cell damage (hemolysis). Our results suggest that operating the LVAD at a fixed rotational speed is not optimal; instead, the pump speed should be adjusted dynamically based on the patient’s physiological needs.

Keywords:assist devices for heart diseases, flow conditions, heart failure, particle image velocimetry, hematologic complications, blood pumping analysis

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