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Tridimenzionalno tiskanje rentgenskega fantoma srca : diplomsko delo
ID Jurša, Laura (Author), ID Kramer, Maša (Author), ID Mekiš, Nejc (Mentor) More about this mentor... This link opens in a new window, ID Boc, Anja (Comentor), ID Starc, Tina (Reviewer)

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Abstract
Uvod: Bolezni koronarnih arterij predstavljajo tretji najpogostejši vzrok smrti v svetu. Za diagnostiko in zdravljenje zožitev koronarnih arterij se primarno uporabljata znotrajžilna koronarografija in koronaroplastika. Rentgenski fantomi imajo pri učenju anatomije koronarnih arterij in projekcij, ki se uporabljajo pri koronarografiji, pomembno vlogo. Tehnologija tridimenzionalnega tiskanja ponuja možnost izdelave specifičnih, cenovno ugodnih in anatomsko ustreznih fantomov, ki lahko pripomorejo k izboljšanju učnega procesa v interventni radiologiji. Namen: Namen našega diplomskega dela je bil izdelati anatomsko ustrezen rentgenski fantom srca s koronarnimi arterijami, ki bi bil uporaben kot učni pripomoček za učenje anatomije in projekcij pri invazivni koronarni angiografiji. Metode dela: Uporabili smo deskriptivno in eksperimentalno metodo dela. Za pripravo teoretičnih izhodišč smo izvedli pregled strokovne literature. V eksperimentalnem delu smo izdelali fantom srca. Izdelava je obsegala štiri faze: načrtovanje, oblikovanje koncepta, oblikovanje modela in preverjanje). S programom 3D Slicer smo izvedli segmentacijo računalniških tomografskih slik in tako ustvarili tridimenzionalen model srca. Model smo natisnili s tehniko ciljanega nalaganja, pri čemer smo uporabili plastičen filament iz polilaktične kisline, ki je omogočil optimalen prikaz struktur na rentgenskih slikah. Naris koronarnih arterij smo izvedli z nanašanjem mešanice ultravijoličnega gela in kovinskega prahu. Izvedli smo tudi rentgensko slikanje in primerjavo pridobljenih slik z referenčnimi koronarogrami iz literature. Rezultati: Uspešno smo izdelali votel, anatomsko pravilen model srca z rentgensko jasno vidnim potekom koronarnih arterij. Rentgenske slike fantoma so, pri prikazu desne in leve koronarne arterije ter njunih vej, pokazale dobro primerljivost s slikami iz literature. Razprava in zaključek: Z raziskavo smo potrdili, da je s segmentacijo računalniško tomografskih slik in tridimenzionalnega tiskanja mogoče izdelati anatomsko ustrezen rentgenski fantom srca, primeren za poučevanje anatomije in učenje projekcij pri koronarografiji. Kljub uspešni izvedbi ostajajo določene omejitve, zlasti pri ponovljivosti in standardizaciji zarisovanja koronarnih arterij. V prihodnosti bi bilo zato smiselno raziskati avtomatizacijo tega koraka. Prav tako bi bilo smiselno preučiti različne materiale, ki bi predstavljali tkivni ekvivalent in s tem omogočili še bolj realističen prikaz organa na rentgenskih slikah.

Language:Slovenian
Keywords:diplomska dela, radiološka tehnologija, koronarografija, invazivna koronarna angiografija, koronarne arterije, segmentacija medicinskih slik, tridimenzionalno tiskanje, rentgenski fantom
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:ZF - Faculty of Health Sciences
Place of publishing:Ljubljana
Publisher:[L. Jurša : M. Kramer]
Year:2025
Number of pages:37 str.
PID:20.500.12556/RUL-170431 This link opens in a new window
UDC:616-07
COBISS.SI-ID:242233859 This link opens in a new window
Publication date in RUL:05.07.2025
Views:291
Downloads:86
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Secondary language

Language:English
Title:Three-dimensional printing of an X-ray phantom of the heart : diploma work
Abstract:
Introduction: Coronary artery disease is the third most common cause of death in the world. Invasive coronary angiography is the primary imaging modality used for both diagnosis and treatment of narrowed or occluded coronary arteries. X-ray phantoms play a crucial role in learning coronary artery anatomy and projections used in coronary angiography. Three-dimensional printing offers a novel approach to develop specific, inexpensive and anatomically accurate phantoms that can improve the learning process in various medical fields, including interventional radiology. Purpose: The purpose of the study was to create an anatomically accurate radiographic phantom showing the heart and coronary arteries that can be used as a teaching tool for learning anatomy and image projections in invasive coronary angiography. Methods: Descriptive and experimental methods were used in the study. The literature review was used to create the theoretical background. The process of model development included four phases: Planning, Concept development, model designing and validation. The computed tomography images were segmented using 3D Slicer software, resulting in a three-dimensional model of the heart. The model was printed using the polylactic acid filament and fused deposition modelling technique. Visualization of the coronary arteries was achieved by applying a mixture of ultraviolet gel and metal powder. Radiographs (on a C-arm) were also taken and the resulting images were compared with reference coronary angiograms from the literature. Results: A hollow, anatomically accurate heart model with clearly visible coronary artery pathways was successfully produced. The X-ray images of the phantom showed good comparability with reference images from the literature. Discussion and conclusion: The study confirms that an anatomically accurate model suitable for teaching anatomy and learning projection techniques in coronary angiography can be produced using computed tomography image segmentation and three-dimensional printing. Despite the successful implementation, certain limitations remain, particularly in the visualization of the coronary arteries. It would therefore make sense to automate this step. In the future, different materials simulating tissue-equivalent properties can also be investigated, which could allow a more realistic representation of the organ and other structures on X-ray images.

Keywords:diploma theses, radiologic technology, coronarography, invasive coronary angiography, coronary arteries, medical image segmentation, three-dimensional printing, X-ray phantom

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