In the scope of this Master's thesis, a range of (hetero)aromatic O-carbamates were prepared from their corresponding hydroxy(hetero)aromatics. O-Carbamates of electron-rich and electron-deficient systems were synthesised. These compounds were isotopically labelled with the use of lithium bases and D$_2$O as a source of deuterium. In this step, the carbamate group functioned as a directing group for ortho-deuteration. It was found that most of the starting O-carbamates were successfully labelled under these conditions. The deuteration was also successfully performed on a larger molecule, which represents an intermediate in the synthesis of the anti-cancer drug momelotinib.
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