Effect of strontium-doped titanium implants on the osseointegration – a systematic review

Ali, Syed Ahmed (author), Ali, Yumna (author), Sadaf, Mahrukh (author)

Strontium has been regarded as an influential osteoblastic characteristic and potentially significantly affects implant osseointegration. However, the exact mechanism of action is unclear. This systematic review aims to evaluate the efficacy of Sr-doped titanium implants in enhancing osseointegration with bone. Research articles were retrieved through electronic databases (Google Scholar, Pub-Med, EMBASE, ELSEVIER, SAGE, and Cochrane Central Register of Controlled Trials) from January 2014 to December 2023. The significant findings were the Bone-to-implant contact (BIC) and New Bone formation (BF). One thousand one hundred twenty-three studies have been found of which eight were selected based on inclusion criteria. All of the in-vivo studies disclosed the effectiveness of Sr-coated Titanium implants in enhancing osseointegration, which was evaluated by analyzing BIC and BF of implants placed in animals. According to the selected studies, the outcomes showed a productive influence of Sr release on the osseointegration and bone formation of an implant with the bone. Further research should be carried out to find the exact mechanism.

• Language: English
• Keywords: osseointegration, strontium, strontium doping, titanium, in-vivo, implants
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: FS - Faculty of Mechanical Engineering
• Publication status: Published
• Publication version: Version of Record
• Year: 2024
• Number of pages: 16 str.
• Numbering: Vol. 8, no. 9
• PID: 20.500.12556/RUL-168225
• UDC: 616.31:620.1
• ISSN on article: 2948-2453
• COBISS.SI-ID: 210849795
• Publication date in RUL: 03.04.2025

Record is a part of a journal

• Title: Periodontal and implant research
• Shortened title: Periodontal implant res.
• Publisher: Springer Nature Switzerland AG
• ISSN: 2948-2453
• COBISS.SI-ID: 202190595

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Keywords: oseointegracija, stroncij, titan, vsadki, implantanti