Prevalence and potential risk factors associated with ketosis in dairy farms in Egypt

Marzok, Mohamed (author), El-Khodery, Sabry (author), Babiker, Hussein (author), Afifi, Ghada G. (author), Abdelaal, Ahmed M. (author), Venugopala, Katharigatta N. (author), Kandeel, Mahmoud (author), Elgioushy, Magdy (author)

Ketosis is an energy-related metabolic disease that primarily occurs during the early lactation period in dairy cattle. Ketosis adversely affects production, animal health, and reproduction. The present study determines the prevalence and risk factors associated with ketosis in dairy cattle during early lactation in Egypt. A total of 1179 dairy cows from 37 dairy farms were screened for ketosis using a semi-quantitative cow-side milk strip test. A questionnaire was constructed to include the hypothesized risk factors. Risk factors were assessed on both the cow and herd levels using logistic regression model. The findings showed that the prevalence of ketosis was 6.35% (75/1179 cases). On the cow level, the final logistic regression model revealed a significant association between ketosis and parity ≥4 (P= 0.040, OR: 1.74, CI 95%: 1.025–2.95), cows with a dry period length ≥ 65 days (P =0.02, OR: 1.88, CI 95%: 1.1–3.18), calving season (P=0.037, OR: 1.73, CI 95%: 1.03–2.89), BCS>3.5 (P= 0.010, OR: 2.03, CI 95%: 1.19–3.47), milk yield ≥25L/day (P= 0.033, OR 2.04, CI 95%: 1.06-3.92), dystocia (P< 0.001; OR: 3.18, CI 95%: 1.75–5.77), retained placenta (P= 0.006, OR: 2.85, CI 95%: 1.35-6.032), and displaced abomasum (P< 0.001, OR: 26.28; CI 95%: 7.20–95.90). On the herd level, there was an association between ketosis and insufficient prepartum feeding of a total mixed ration (P= 0. 021, OR: 6.29, CI 95%: 1.325–29.86), and in herds deficient-lactation supplementa­tion propylene glycol (P= 0.047, OR: 4.86, CI 95%: 1.020–23.19). In conclusion, ketosis is an existing problem in dairy farms in Egypt; therefore, identification of risk factors may provide a useful approach for the prevention and control such metabolic problems.

• Language: English
• Keywords: dairy cow, ketosis, risk factors, BHBA
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: VF - Veterinary Faculty
• Publication status: Published
• Publication version: Version of Record
• Year: 2024
• Number of pages: Str. 203-214
• Numbering: Vol. 61, no. 3
• PID: 20.500.12556/RUL-168113
• UDC: 636.2:616:612.015.3
• ISSN on article: 1580-4003
• DOI: 10.26873/SVR-1777-2023
• COBISS.SI-ID: 228860419
• Publication date in RUL: 28.03.2025

Record is a part of a journal

• Title: Slovenian veterinary research : the scientific journal of the Veterinary Faculty University of Ljubljana
• Shortened title: Slov. vet. res.
• Publisher: Veterinarska fakulteta, Veterinarska fakulteta, Založba Univerze v Ljubljani
• ISSN: 1580-4003
• COBISS.SI-ID: 108028416

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Title: Razširjenost in potencialni dejavniki tveganja, povezani s ketozo na mlečnih kmetijah v Egiptu

Abstract

Ketoza je z energijo povezana presnovna bolezen, ki se pojavlja predvsem v zgodnjem obdobju laktacije pri kravah molznicah. Ketoza negativno vpliva na proizvodnjo, zdravje živali in reprodukcijo. V tej študiji smo določali razširjenost in dejavnike tveganja, povezane s ketozo pri mlečnem govedu v zgodnji laktaciji v Egiptu. Na ketozo je bilo pregledanih 1179 krav molznic iz 37 mlečnih farm z uporabo semikvantitativnega testa na mlečnem traku. Sestavili smo vprašalnik, ki je vključeval domnevne dejavnike tveganja. Dejavnike tveganja smo ocenili na ravni krave in črede z uporabo logističnega regresijskega modela. Ugotovitve so pokazale, da je bila razširjenost ketoze 6,35 % (75/1179 primerov). Na ravni krave je končni logistični regresijski model pokazal pomembno povezavo med ketozo in pariteto ≥ 4 (P= 0,040, OR: 1,74, CI 95 %: 1,025-2,95), kravami z dolžino sušnega obdobja ≥ 65 dni (P=0,02, OR: 1,88, CI 95 %: 1,1-3,18), sezono telitve (P=0,037, OR: 1,73, CI 95 %: 1,03-2. 89), BCS>3,5 (P= 0,010, OR: 2,03, CI 95 %: 1,19-3,47), mlečnostjo ≥25L/dan (P= 0,033, OR 2,04, CI 95 %: 1,06-3,92), distociji (P< 0,001; OR: 3. 18, CI 95 %: 1,75-5,77), zadržani posteljici (P= 0,006, OR: 2,85, CI 95 %: 1,35-6,032) in dislokacijo siriščnika (P< 0,001, OR: 26,28; CI 95 %: 7,20-95,90). Na ravni črede smo ugotovili povezavo med ketozo in nezadostnim krmljenjem s skupnim mešanim obrokom pred porodom (P= 0. 021, OR: 6,29, CI 95 %: 1,325-29,86), v čredah s pomanjkljivo laktacijo pa z dodatkom propilenglikola (P= 0,047, OR: 4,86, CI 95 %: 1,020-23,19). Zaključimo lahko, da je ketoza obstoječa težava na mlečnih kmetijah v Egiptu, zato lahko opredelitev dejavnikov tveganja predstavlja uporaben pristop za preprečevanje in nadzor teh presnovnih težav.

• Keywords: krava molznica, ketoza, dejavniki tveganja, BHBA

Projects

• Funder: King Faisal University, Saudi Arabia
• Project number: Grant No. 5727