State-of-the-art pulsed field ablation for cardiac arrhythmias : ongoing evolution and future perspective

Chun, Kyoung-Ryul Julian (author), Miklavčič, Damijan (author), Vlachos, Konstantinos (author), Bordignon, Stefano (author), Scherr, Daniel (author), Jaïs, Pierre (author), Schmidt, Boris (author)

Pulsed field ablation (PFA) is an innovative approach in the field of cardiac electrophysiology aimed at treating cardiac arrhythmias. Unlike traditional catheter ablation energies, which use radiofrequency or cryothermal energy to create lesions in the heart, PFA utilizes pulsed electric fields to induce irreversible electroporation, leading to targeted tissue destruction. This state-of-the-art review summarizes biophysical principles and clinical applications of PFA, highlighting its potential advantages over conventional ablation methods. Clinical data of contemporary PFA devices are discussed, which combine predictable procedural outcomes and a reduced risk of thermal collateral damage. Overall, these technological developments have propelled the rapid evolution of contemporary PFA catheters, with future advancements potentially impacting patient care

• Language: English
• Keywords: catheter ablation, energy sources, electroporation, pulsed field
• Work type: Article
• Typology: 1.02 - Review Article
• Organization: FE - Faculty of Electrical Engineering
• Publication status: Published
• Publication version: Version of Record
• Year: 2024
• Number of pages: 14 str.
• Numbering: Vol. 26, iss. 6, art. euae134
• PID: 20.500.12556/RUL-167874
• UDC: 602.621:616.12-089.87
• ISSN on article: 1532-2092
• DOI: 10.1093/europace/euae134
• COBISS.SI-ID: 200274947
• Publication date in RUL: 18.03.2025

Record is a part of a journal

• Title: Europace
• Shortened title: Europace
• Publisher: Harcourt Publishers.
• ISSN: 1532-2092
• COBISS.SI-ID: 1499735

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Keywords: katetrska ablacija, viri energije, elektroporacija, pulzno električno polje

Projects

• Funder: ANR - French National Research Agency
• Funding programme: French National Research Agency (ANR)
• Project number: IHU LIRYC ANR-10-IAHU-04
• Name: French national grant Université de Bordeaux

• Funder: ARIS - Slovenian Research and Innovation Agency