Validation of the Postnatal Growth and Retinopathy of Prematurity (G-ROP) criteria in a Slovenian cohort

Zupan, Matej (author), Binenbaum, Gil (author), Tekavčič Pompe, Manca (author)

Purpose To validate the Postnatal Growth and ROP (G-ROP) study criteria for retinopathy of prematurity (ROP) screening in a Slovenian cohort. Methods We conducted a retrospective cohort study of preterm infants screened in 2021 at the University Medical Centre Ljubljana, Slovenia. The G-ROP criteria were systematically applied. Primary outcomes were sensitivity for ROP requiring treatment, sensitivity for any ROP, and reduction in the number of infants screened. Results Of 102 infants screened, 27 (26.4%) developed ROP. Eleven infants (10.7%) had type 1 ROP, of whom 2 (1.9%) had aggressive ROP; 5 infants (4.9%) had type 2 ROP, and 11 (10.7%) had milder ROP. Using the original or simplified G-ROP criteria, all infants who developed type 1 ROP (sensitivity, 100% [95% CI, 74%-100%]), and all infants who developed ROP (sensitivity, 100% [95% CI, 88%-100%]) were correctly identified. Application of the original G-ROP criteria would have reduced the number of infants screened by 29.4% (30 of 102). Conclusions In our cohort, both the original and simplified G-ROP criteria showed 100% sensitivity for predicting ROP type 1 while reducing the number of unnecessary screenings. These results confirm the reliability of the G-ROP criteria in the Slovenian context and suggest that their use improves screening efficiency.

• Language: English
• Keywords: prematurity, postnatal growth, retinopathy, Slovenia, cohort study
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: MF - Faculty of Medicine
• Publication status: Published
• Publication version: Version of Record
• Year: 2025
• Number of pages: 6 str.
• Numbering: Vol. 29, no. 1, art. 104113
• PID: 20.500.12556/RUL-167660
• UDC: 618.2/.7
• ISSN on article: 1091-8531
• DOI: 10.1016/j.jaapos.2025.104113
• COBISS.SI-ID: 227478787
• Publication date in RUL: 05.03.2025

Record is a part of a journal

• Title: Journal of AAPOS
• Shortened title: J. AAPOS
• Publisher: Elsevier, American Association for Pediatric Ophthalmology and Strabismus
• ISSN: 1091-8531
• COBISS.SI-ID: 1472533

Licences

• License: CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
• Link: http://creativecommons.org/licenses/by-nc-nd/4.0/
• Description: The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.

Secondary language

• Language: Slovenian
• Keywords: nedonošenost, postnatalna rast, retinopatija, Slovenija, kohortna študija