Human herpesvirus Epstein-Barr (EBV) and Its porcine homologs unveil the conser ved mechanism of receptor endocytosis: new insights into viral immune evasion and antiviral therapy potential?

Kubale, Valentina (author)

Over the past two years, the University of Ljubljana and the Republic of Slovenia’s public agency, the Slovenian Research and Innovation Service (ARIS), have acknowledged and celebrated several exceptional accomplishments in viral receptor research. These achievements are considered among the finest by both the University of Ljubljana and ARIS. The significance of these achievements lies in the research findings, which indicate that the EBV-BILF1 receptor encoded by the Epstein-Barr virus (EBV) could become a promising new drug target for EBV. Additionally, the research suggests pigs represent a great model for further investigations (1–4).

• Language: English
• Keywords: Epstein-Barr virus, porcine homologs, receptors, antiviral therapy, swine
• Work type: Article
• Typology: 1.03 - Other scientific articles
• Organization: VF - Veterinary Faculty
• Publication status: Published
• Publication version: Version of Record
• Year: 2024
• Number of pages: Str. 81-84
• Numbering: Vol. 61, no. 2
• PID: 20.500.12556/RUL-166745
• UDC: 616.523:636.4
• ISSN on article: 1580-4003
• DOI: 10.26873/SVR-2053-2024
• COBISS.SI-ID: 221153539
• Publication date in RUL: 23.01.2025

Record is a part of a journal

• Title: Slovenian veterinary research : the scientific journal of the Veterinary Faculty University of Ljubljana
• Shortened title: Slov. vet. res.
• Publisher: Veterinarska fakulteta, Založba Univerze v Ljubljani
• ISSN: 1580-4003
• COBISS.SI-ID: 108028416

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 25.01.2025

Secondary language

• Language: Slovenian
• Title: Humani herpesvirus Epstein-Barr (EBV) in njegovi prašičji homologi razkrivajo ohranjeni mehanizem receptorske endocitoze: nov vpogled v virusno izmikanje imunskemu sistemu in potencialne protivirusne terapije?

Abstract

Univerza v Ljubljani in Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije (ARIS) sta v preteklih dveh letih prepoznali in počastili več izjemnih dosežkov na področju raziskovanja virusnih receptorjev. Ti dosežki – tako na Univerzi v Ljubljani kot na ARIS-u – sodijo med najboljše. Njihov pomen izhaja iz raziskav, ki kažejo na to, da bi se lahko receptor EBV-BILF1, kodiran na virusu Epstein-Barr (EBV), uporabljal kot obetavna nova tarča za zdravljenje EBV. Poleg tega raziskava predlaga uporabo prašičev kot modela za nadaljnje preiskave (1–4).